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Lipid-lowering agents, also sometimes referred to as hypolipidemic agents, cholesterol-lowering drugs, or antihyperlipidemic agents are a diverse group of pharmaceuticals that are used to lower the level of lipids and lipoproteins, such as cholesterol, in the blood (hyperlipidemia). The American Heart Association recommends the descriptor ...
This includes familial hypercholesterolemia (high cholesterol), familial hypertriglyceridemia (high triglycerides), and familial combined hyperlipidemia (high levels of both cholesterol and ...
Evolocumab, [6] sold under the brand name Repatha, is a monoclonal antibody that is an immunotherapy medication for the treatment of hyperlipidemia.. Evolocumab is a fully human monoclonal antibody that inhibits proprotein convertase subtilisin/kexin type 9 (PCSK9).
Mixed hyperlipidemia, in combination with fenofibrate; Homozygous familial hypercholesterolemia, in combination with specific statins; Homozygous sitosterolemia; A 2018 review found that ezetimibe used as sole treatment slightly lowered plasma levels of lipoprotein(a), but the effect was not large enough to be important. [22]
High cholesterol can be treated with medication and/or lifestyle changes. “The treatment depends on the patient,” Dr. Adedinsewo explains. “We consider your age and medical history ...
About a third of American adults have high LDL cholesterol -- that's the bad kind -- but less than half of adults with high LDL seek treatment, according to the Centers for Disease Control and ...
High cholesterol levels have been associated with cardiovascular disease. [8] There are various forms of statins, some of which include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin. [9] Combination preparations of a statin and another agent, such as ezetimibe/simvastatin, are also available.
Pharmacological intervention can be considered in dyslipidemia. Based on the Framingham Risk Scores, there are different thresholds that indicate whether treatment should be initiated. Individuals with a score of 20% are considered to have a high cardiovascular risk, a score of 10–19% indicates an intermediate risk, and patients with a score ...
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