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A chemotherapy regimen is a regimen for chemotherapy, defining the drugs to be used, their dosage, ... cisplatin, etoposide (VP-16) aggressive relapsed lymphomas, ...
For example, the CHOP regimen consists of cyclophosphamide, doxorubicin, vincristine and prednisone. Besides chemotherapy, medical oncology (pharmacotherapy for cancer) includes several noncytotoxic classes of therapy, such as hormonal therapy and targeted therapy (biologic therapy). Those agents are described in the relevant articles.
Etoposide, an epipodophyllotoxin topoisomerase inhibitor; Solu-Medrol - Methylprednisolone, which is a glucocorticoid that can lyse lymphocytes; High-dose Ara-C - cytarabine; Platinol - Cisplatin, a platinum-based antineoplastic agent, also an alkylating antineoplastic agent.
Carboplatin can also be used as a substitute when patient is intolerant of cisplatin. [23] Other chemotherapy regimens including Paclitaxel and Topoisomerase I Inhibitors: Topotecan (Hycamtin) and Irinotecan (Camptosar) also reported significant response against limited-stage small-cell carcinoma during clinical trials. [24]
Cisplatin is administered intravenously as short-term infusion in normal saline for treatment of solid and haematological malignancies. It is used to treat various types of cancers, including sarcomas, some carcinomas (e.g., small cell lung cancer, squamous cell carcinoma of the head and neck and ovarian cancer), lymphomas, bladder cancer, cervical cancer, [9] and germ cell tumors.
In combination with etoposide and either carboplatin or cisplatin, as first-line treatment for adults with extensive-stage small cell lung cancer. In combination with gemcitabine and cisplatin for adults with locally advanced or metastatic biliary tract cancer (BTC).
HDC is known to be effective in treating types of cancer and has been found to enhance patient outcomes. This treatment method is commonly linked with blood cancers like multiple myeloma, Hodgkin's lymphoma, and non-Hodgkin's lymphoma. It is also used in solid tumors such as germ cell tumors and certain high risk or recurrent breast cancers.
Electrochemotherapy is the combined treatment in which injection of a chemotherapeutic drug is followed by application of high-voltage electric pulses locally to the tumor. The treatment enables the chemotherapeutic drugs, which otherwise cannot or hardly go through the membrane of cells (such as bleomycin and cisplatin), to enter the cancer cells.
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