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  2. Demyelinating disease - Wikipedia

    en.wikipedia.org/wiki/Demyelinating_disease

    Quantitative proton magnetic resonance spectroscopy (MRS) is a noninvasive analytical technique that has been used to study metabolic changes in brain tumors, strokes, seizure disorders, Alzheimer's disease, depression, and other diseases affecting the brain. It has also been used to study the metabolism of other organs such as muscles.

  3. Childhood dementia - Wikipedia

    en.wikipedia.org/wiki/Childhood_dementia

    Childhood dementia is an umbrella group of rare, mostly untreatable neurodegenerative disorders that show symptoms before the age of 18. These conditions cause progressive deterioration of the brain and the loss of previously acquired skills such as talking, walking, and playing.

  4. Hashimoto's thyroiditis - Wikipedia

    en.wikipedia.org/wiki/Hashimoto's_thyroiditis

    Hashimoto's thyroiditis is a T-lymphocyte mediated attack on the thyroid gland. [15] T helper 1 cells trigger macrophages and cytotoxic lymphocytes to destroy thyroid follicular cells, while T helper 2 cells stimulate the excessive production of B cells and plasma cells which generate antibodies against the thyroid antigens, leading to ...

  5. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Hypothyroidism (also called underactive thyroid, low thyroid or hypothyreosis) is a disorder of the endocrine system in which the thyroid gland does not produce enough thyroid hormones. [3] It can cause a number of symptoms, such as poor ability to tolerate cold , extreme fatigue, muscle aches , constipation , slow heart rate , depression , and ...

  6. Niemann–Pick disease type C - Wikipedia

    en.wikipedia.org/wiki/Niemann–Pick_disease_type_C

    Cholesterol is a major component of cell plasma membranes, which define the cell as a whole and its organelles. It is also the basic building block of steroid hormones , including neurosteroids . In Niemann–Pick type C, large amounts of free or unesterified cholesterol accumulate in lysosomes, and leads to relative deficiency of this molecule ...

  7. Parafollicular cell - Wikipedia

    en.wikipedia.org/wiki/Parafollicular_cell

    Parafollicular cells, also called C cells, are neuroendocrine cells in the thyroid. They are called C cells because the primary function of these cells is to secrete calcitonin. [1] They are located adjacent to the thyroid follicles and reside in the connective tissue. These cells are large and have a pale stain compared with the follicular cells.

  8. Memory disorder - Wikipedia

    en.wikipedia.org/wiki/Memory_disorder

    Alzheimer's disease (AD) is a progressive, degenerative and fatal brain disease, in which cell to cell connections in the brain are lost. Alzheimer's disease is the most common form of dementia. [2] Globally approximately 1–5% of the population is affected by Alzheimer's disease. [3] Women are disproportionately affected by Alzheimer's disease.

  9. Cerebral atrophy - Wikipedia

    en.wikipedia.org/wiki/Cerebral_atrophy

    Many diseases that cause cerebral atrophy are associated with dementia, seizures, and a group of language disorders called the aphasias. Dementia is characterized by a progressive impairment of memory and intellectual function that is severe enough to interfere with social and work skills. Memory, orientation, abstraction, ability to learn ...