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Prasterone, also known as dehydroepiandrosterone (DHEA) and sold under the brand name Intrarosa among others, is a medication as well as over-the-counter dietary supplement which is used to correct DHEA deficiency due to adrenal insufficiency or old age, as a component of menopausal hormone therapy, to treat painful sexual intercourse due to vaginal atrophy, and to prepare the cervix for ...
A 2005 placebo-controlled study looked at men and women aged 45 to 65 with midlife-onset major or minor depression. Participants followed a six-week DHEA treatment plan that included 90 milligrams ...
Plasma levels of DHEA in adult men are 10 to 25 nM, in premenopausal women are 5 to 30 nM, and in postmenopausal women are 2 to 20 nM. [25] Conversely, DHEA-S levels are an order of magnitude higher at 1–10 μM. [25] Levels of DHEA and DHEA-S decline to the lower nanomolar and micromolar ranges in men and women aged 60 to 80 years. [25]
In addition, there is strong evidence that continuous micronized DHEA 25 mg TID reduces miscarriage and aneuploidy rates, especially above age 35. [45] A combined pentoxifylline-tocopherol treatment has been reported effective in improving uterine parameters in women with POF undergoing IVF with donor oocytes (IVF-OD). Three women with uterine ...
Older women struggling to conceive often find hope in an over-the-counter steroid hormone supplement called DHEA. Though evidence for its effectiveness is weak, DHEA has rocketed to prominence as ...
ST. LOUIS, MO (KTVI) – If you want to get pregnant, you might want to think twice about popping a painkiller. New research shows it could impact a woman's fertility. Dr. Emily Jungheim, a ...
DHEA is an androgen precursor that lacks FDA and Health Canada approval for use in women, and is not available in Canada as a pharmaceutical preparation; [26] it is sold as an over-the-counter drug or incorporated into compounded preparations in the United States. In the body, it can be converted into testosterone then estrogen; there are no ...
7-Ketodehydroepiandrosterone (7-keto-DHEA, 7-oxo-DHEA), also known as 7-oxoprasterone, is a steroid prohormone produced by metabolism of the prohormone dehydroepiandrosterone (DHEA). [ 1 ] [ 2 ] Pharmacodynamics
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