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Skin color contrast has been identified as a feminine beauty standard observed across multiple cultures. [7] Women tend to have darker eyes and lips than men, especially relative to the rest of their facial features, and this attribute has been associated with female attractiveness and femininity, [7] yet it also decreases male attractiveness according to one study. [8]
MCHC can be normal even when hemoglobin production is decreased (such as in iron deficiency) due to a calculation artifact. MCHC can be elevated ("hyperchromic") in hereditary spherocytosis , sickle cell disease and homozygous hemoglobin C disease , depending upon the hemocytometer.