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2. How Many Years Can I Take Cialis? - AOL

   www.aol.com/many-years-cialis-105700599.html

   Some people might also wonder whether Cialis could lose effectiveness over time. While some users might argue that they need to increase their dosage, generally speaking, there’s no research to ...

3. Tadalafil - Wikipedia

   en.wikipedia.org/wiki/Tadalafil

   One advantage Cialis has over Viagra and Levitra is its 17.5-hour half-life (thus Cialis is advertised to work for up to 36 hours, [32] after which time there remains approximately 25% of the absorbed dose in the body) when compared to the four-hour half-life of sildenafil (Viagra).

4. Cialis vs. Viagra: How Are They Different? - AOL

   www.aol.com/cialis-vs-viagra-different-175700354...

   As we mentioned, most of the time, side effects from ED medications get better over time. But because Cialis has a much longer half-life than Viagra, you may experience Cialis side effects for longer.

5. Cialis Side Effects: What to Expect (& How to Avoid Them) - AOL

   www.aol.com/cialis-side-effects-expect-avoid...

   Most of the time, Cialis-induced headaches are mild and become less intense over time. That said, Cialis’s long half-life means a dull headache might stick around for several hours after the fun ...

6. Therapeutic index - Wikipedia

   en.wikipedia.org/wiki/Therapeutic_index

   The effective therapeutic index can be affected by targeting, in which the therapeutic agent is concentrated in its desirable area of effect. For example, in radiation therapy for cancerous tumors, shaping the radiation beam precisely to the profile of a tumor in the "beam's eye view" can increase the delivered dose without increasing toxic ...

7. Comparison of birth control methods - Wikipedia

   en.wikipedia.org/wiki/Comparison_of_birth...

   Side effects from hormonal contraceptives typically disappear over time (3-5 months) with consistent use. [16] Less common effects of combined hormonal contraceptives include increasing the risk of deep vein thrombosis to 2-10 per 10,000 women per year and venous thrombotic events (see venous thrombosis) to 7-10 per 10,000 women per year. [15]

8. 4 Common ED Pills: Weighing the Pros & Cons of Each - AOL

   www.aol.com/4-common-ed-pills-weighing-141800609...

   The Best ED Medication for Men: Pros & Cons of Top ED Pills. Over the last 25 years, (ED) medications like Viagra and Cialis have become common fixtures in bedrooms around the world.

9. Sildenafil - Wikipedia

   en.wikipedia.org/wiki/Sildenafil

   Sildenafil, sold under the brand name Viagra among others, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension. [4] [8] It is also sometimes used off-label for the treatment of certain symptoms in secondary Raynaud's phenomenon. [9]