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The smallpox vaccine is used to prevent smallpox infection caused by the variola virus. [10] It is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus.
Smallpox is the first disease, and so far the only infectious disease of humans, to be eradicated by deliberate intervention. [6] It became the first disease for which there was an effective vaccine in 1798 when Edward Jenner showed the protective effect of inoculation (vaccination) of humans with material from cowpox lesions. [10]
Most of the time it is treated with antibiotics, but many strains have become resistant to the antibiotics used to treat these infections. In some areas of the United States, up to 15% of infections are resistant to penicillin. With is success of the pneumococcal disease vaccine, much less antibiotic-resistant infections have been seen. [36]
It’s only some consolation that in this particular case, it all turned out okay: the little boy didn’t get sick, because his body had become immune to the smallpox virus. Thus a vaccine was ...
Vaccination is treatment of an individual with an attenuated (i.e. less virulent) pathogen or other immunogen, whereas inoculation, also called variolation in the context of smallpox prophylaxis, is treatment with unattenuated variola virus taken from a pustule or scab of a smallpox patient into the superficial layers of the skin, commonly the ...
Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.
According to the CDC, monkeypox is closely related to the virus that causes smallpox. Both the CDC and the WHO have published data showing that the smallpox vaccine is 85% effective in preventing ...
The term variolation refers solely to inoculation with smallpox virus and is related to but not interchangeable with vaccination. The latter term was first used in 1800 soon after Edward Jenner introduced smallpox vaccine derived from cowpox, an animal disease distinct from smallpox.