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Uterine hyperstimulation or hypertonic uterine dysfunction is a potential complication of labor induction. This is displayed as Uterine tachysystole - the contraction frequency numbering more than five in a 10-minute time frame or as contractions exceeding more than two minutes in duration. [ 1 ]
Uterine muscle contractions are induced via a G-protein pathway stemming from the oxytocin receptor (OXTR), the binding and activation site of oxytocin. [7] When oxytocin binds to its associated receptors in the uterus, a cascade is initiated that results in an increase in calcium and subsequently an increase in muscle contractions.
The suppression of contractions is often only partial and tocolytics can only be relied on to delay birth for a matter of days. Depending on the tocolytic used, the pregnant woman or fetus may require monitoring (e.g., blood pressure monitoring when nifedipine is used as it reduces blood pressure; cardiotocography to assess fetal well-being).
Uterine Tachysystole is a condition of excessively frequent uterine contractions during pregnancy. [1] It is most often seen in induced or augmented labor, though it can also occur during spontaneous labor, [2] and this may result in fetal hypoxia and acidosis. This may have serious effects on both the mother and the fetus including ...
Hyperactive or hypertonic uterus; Vaginal delivery is contraindicated (e.g., invasive cervical carcinoma, active genital herpes infection, total placenta previa, vasa previa, cord presentation or prolapse) Uterine or cervical scarring from previous cesarean section or major cervical or uterine (e.g., transfundal) surgery; Unengaged fetal head
Contractions of the uterus require energy, so the longer the mother is in labor the more energy she expends. When the mother is depleted of energy, the contractions become weaker and labor will become increasingly longer. [1] Antibiotics are also an important treatment as infection is a possible result of obstructed labor. [11]
Amnioinfusion is a method in which isotonic fluid is instilled into the uterine cavity.. It was introduced in the 1960s as a means of terminating pregnancy and inducing labor in intrauterine death, but is currently used as a treatment in order to correct fetal heart rate changes caused by umbilical cord compression, indicated by variable decelerations seen on fetal heart rate monitoring.
Montevideo units are calculated by obtaining the peak uterine pressure amplitude and subtracting the resting tone. Then adding up those numbers generated by each contraction within a 10-minute window. For example, five contractions occurred, producing peak pressures of 55, 50, 45, 65, and 50 mm Hg, respectively.