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Pomalidomide, sold under the brand names Pomalyst and Imnovid, [7] [8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma. [ 7 ] Pomalidomide was approved for medical use in the United States in February 2013, [ 10 ] and in the European Union in August 2013. [ 8 ]
AEIOU-TIPS is a mnemonic acronym used by some medical professionals to recall the possible causes for altered mental status.Medical literature discusses its utility in determining differential diagnoses in various special populations presenting with altered mental status including infants, [1] children, [2] adolescents, [3] and the elderly. [4]
Sudden unexplained death in childhood (SUDC) is the death of a child over the age of 12 months which remains unexplained after a thorough investigation and autopsy. There has not been enough research to identify risk factors, common characteristics, or prevention strategies for SUDC. SUDC is similar in concept to sudden infant death syndrome ...
Because many organs can be affected by myeloma, the symptoms and signs vary greatly. Fatigue and bone pain are the most common symptoms at presentation. The CRAB criteria were formerly the benchmark used to establish the presence of active multiple myeloma (as opposed to an earlier, generally asymptomatic, "smoldering" form of the disease).
The first symptoms of neuroleptic malignant syndrome are usually muscle cramps and tremors, fever, symptoms of autonomic nervous system instability such as unstable blood pressure, and sudden changes in mental status (agitation, delirium, or coma). Other possible symptoms include sweating, trouble swallowing, tremors, incontinence, and mutism.
A decreased level of consciousness correlates to increased morbidity (sickness) and mortality (death). [5] Thus it is a valuable measure of a patient's medical and neurological status. In fact, some sources consider level of consciousness to be one of the vital signs. [3] [6]
Confusion, ophthalmoplegia, ataxia: Wernicke encephalopathy: Whipple's Triad: Hypoglycaemia during attacks, resolution of symptoms upon correction of blood glucose, symptoms brought about by low glucose states. Insulinoma: Triad of Aortic stenosis: Chest pain, Heart failure, Syncope: Aortic stenosis: Murphy's triad: Pain-> Vomiting -> Fever ...
Alcohol can exacerbate the symptoms and may directly contribute to increased severity of symptoms. The reasons for toxicity vary depending on the mixture of drugs. Usually, most victims die after using two or more drugs in combination that suppress breathing, and the low blood oxygen level causes brain death .