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The Gamma variant (P.1) [a] was [6] [7] one of the variants of SARS-CoV-2, the virus that causes COVID-19. [8] This variant of SARS-CoV-2 has been named lineage P.1 and has 17 amino acid substitutions, ten of which in its spike protein, including these three designated to be of particular concern: N501Y, E484K and K417T.
A 2010 review study by Puren et al. [2] categorizes viral load testing into three types: (1) nucleic acid amplification based tests (NATs or NAATs) commercially available in the United States with Food and Drug Administration (FDA) approval, or on the market in the European Economic Area (EEA) with the CE marking; (2) "Home–brew" or in-house NATs; (3) non-nucleic acid-based test.
COVID-19 is more infectious than influenza, but less so than measles. [34] Estimates of the number of people infected by one person with COVID-19—the basic reproduction number (R 0)—have varied. In November 2020, a systematic review estimated R 0 of the original Wuhan strain to be approximately 2.87 (95% CI, 2.39 – 3.44). [90]
Iota variant, [188] also known as lineage B.1.526, is one of the variants of SARS-CoV-2, the virus that causes COVID-19. It was first detected in New York City in November 2020. The variant has appeared with two notable mutations: the E484K spike mutation, which may help the virus evade antibodies, and the S477N mutation, which helps the virus ...
Around the globe, a new strain of COVID-19 is spreading exponentially. The COVID-19 XEC variant is derived from Omicron strains KS.1.1 and KP.3.3, says Dr. Francesca Torriani, MD, an infectious ...
Masitinib was found to inhibit SARS-CoV-2 main protease, showing a greater than 200-fold reduction in viral titers in the lungs and nose of mice, however it is not approved for the treatment of COVID-19 in humans.
Coronavirus disease 2019 (COVID-19) is a contagious disease caused by the coronavirus SARS-CoV-2. In January 2020, the disease spread worldwide, resulting in the COVID-19 pandemic . The symptoms of COVID‑19 can vary but often include fever, [ 7 ] fatigue, cough, breathing difficulties , loss of smell , and loss of taste .
The Delta variant (B.1.617.2) was [3] [4] a variant of SARS-CoV-2, the virus that causes COVID-19. It was first detected in India on 5 October 2020. It was first detected in India on 5 October 2020. The Delta variant was named on 31 May 2021 and had spread to over 179 countries by 22 November 2021.