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  2. Gate control theory - Wikipedia

    en.wikipedia.org/wiki/Gate_control_theory

    Combining early concepts derived from the specificity theory and the peripheral pattern theory, the gate control theory is considered to be one of the most influential theories of pain. This theory provided a neural basis which reconciled the specificity and pattern theories -- and ultimately revolutionized pain research.

  3. Ronald Melzack - Wikipedia

    en.wikipedia.org/wiki/Ronald_Melzack

    Melzack and Wall noticed that some individuals felt immense pain when damage to the body was minimal, and some people with traumatic injuries experienced little or no pain until a later time. [ 8 ] In 1965 at MIT , Melzack and Wall developed the gate control theory of pain [ 9 ] which states that pain is "gated" or modulated by past experience.

  4. Patrick D. Wall - Wikipedia

    en.wikipedia.org/wiki/Patrick_D._Wall

    At Melzack's urging they wrote a paper on the Gate control theory of pain and published it in Brain in 1962; according to Wall it was read by around three people. After expanding and rewriting the article they republished it as Pain Mechanisms: a new theory in Science in 1965 where it drew wider attention, with mostly negative comments. [11]

  5. Pain theories - Wikipedia

    en.wikipedia.org/wiki/Pain_theories

    Modern research has gathered considerable amounts of evidence that support the theory that pain is not only a physical phenomenon but rather a biopsychosocial phenomenon, encompassing culture, nociceptive stimuli, and the environment in the experience and perception of pain. For example, the Sun Dance is a ritual performed by traditional groups ...

  6. Textbook of Pain - Wikipedia

    en.wikipedia.org/wiki/Textbook_of_Pain

    Wall & Melzack's Textbook of Pain is a medical textbook published by Elsevier. It is named after Patrick David Wall and Ronald Melzack, who introduced the gate control theory into pain research in the 1960s. First released in 1984, the book has been described as "the most comprehensive scientific reference text in the field of pain medicine". [1]

  7. Synaptic gating - Wikipedia

    en.wikipedia.org/wiki/Synaptic_gating

    Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic ...

  8. Neuropathic pain - Wikipedia

    en.wikipedia.org/wiki/Neuropathic_pain

    Gate control theory of pain. A major hypothesis in the theory of pain perception is the gate control theory of pain, proposed by Wall and Melzack in 1965. The theory predicts that the activation of central pain inhibitory neurons by non-pain sensing neurons prevents the transmission of non-harmful stimuli to pain centers in the brain.

  9. Spinal cord stimulator - Wikipedia

    en.wikipedia.org/wiki/Spinal_cord_stimulator

    Electrotherapy of pain by neurostimulation began shortly after Melzack and Wall proposed the gate control theory in 1965. This theory proposed that nerves carrying painful peripheral stimuli and nerves carrying touch and vibratory sensation both terminate in the dorsal horn (the gate) of spinal cord. [21]

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