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Friability testing is a laboratory technique used by the pharmaceutical industry to test the durability of tablets during transit. This testing involves repeatedly dropping a sample of tablets over a fixed time, using a rotating wheel with a baffle.
It is similar to friability testing, [1] but they are not the same thing. Tablet hardness testers first appeared in the 1930s. [3] In the 1950s, the Strong-Cobb tester was introduced. It was patented by Robert Albrecht on July 21, 1953. [4] and used an air pump. The tablet breaking force was based on arbitrary units referred to as Strong-Cobbs. [3]
The basic tests measure the following parameters: wet tensile strength, cone jolt, mouldability, friability, moisture content, permeability, green compression strength, compactibility, loss on ignition, volatiles content, grain size & distribution, dust (dead clay) content, and active clay content, impact strength .
Friability and abrasion testing is performed in rotating testing drums, designed according to the pharmacopeia. The measured parameter is weight loss before and after testing and tumbling the tablets at a particular time and speed. In the friability test drum tablets are being carried up by a "shovel" and dropped.
When a test fails to meet the thickness and other test requirements that are in place to ensure plane strain conditions, the fracture toughness value produced is given the designation . Fracture toughness is a quantitative way of expressing a material's resistance to crack propagation and standard values for a given material are generally ...
Hardgrove Grindability Index (short HGI) is a measure for the grindability of coal.Grindability is an index, therefore it has no unit. The smaller the HGI, the harder is coal texture and less grindable is the coal.
The current edition of the British Pharmacopoeia comprises six volumes, which contain nearly 3,000 monographs for drug substances, excipients, and formulated preparation, together with supporting general notices, appendices (test methods, reagents etc.), and reference spectra, used in the practice of medicine, all comprehensively indexed and ...
Triaxial apparatus with sample attached ready for testing. In materials science, a triaxial shear test is a common method to measure the mechanical properties of many deformable solids, especially soil (e.g., sand, clay) and rock, and other granular materials or powders.