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  2. Edmonton protocol - Wikipedia

    en.wikipedia.org/wiki/Edmonton_protocol

    The first patient was treated using the Edmonton protocol in March 1999. The protocol was first published in the New England Journal of Medicine in July 2000. [1] The NEJM report was exciting for the diabetes field because the seven patients undergoing the Edmonton protocol remained insulin-independent after an average of 12 months. [citation ...

  3. Methylprednisolone - Wikipedia

    en.wikipedia.org/wiki/Methylprednisolone

    Methylprednisolone (Depo-Medrol, Medrol, Solu-Medrol) is a synthetic glucocorticoid, primarily prescribed for its anti-inflammatory and immunosuppressive effects. [4] [5] [6] It is either used at low doses for chronic illnesses or used concomitantly at high doses during acute flares.

  4. Steroid-induced diabetes - Wikipedia

    en.wikipedia.org/wiki/Steroid-induced_diabetes

    The American Diabetes Association defines the following criteria for the diagnosis of diabetes: a HbA1c of 6.5%, an 8-hour fasting blood glucose of 7.0 mmol/L (126 mg/dL), a 2-hour oral glucose tolerance test (OGTT) of ≥ 11.1 mmol/L (200 mg/dL), or in patients exhibiting hyperglycemic symptoms, a random plasma glucose of ≥ 11.1 mmol/L (200 mg/dL).

  5. Methylprednisolone succinate - Wikipedia

    en.wikipedia.org/wiki/Methylprednisolone_succinate

    Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 succinate ester of methylprednisolone—which is used by intravenous administration.

  6. Subcutaneous administration - Wikipedia

    en.wikipedia.org/wiki/Subcutaneous_administration

    The gauge of the needle used can range from 25 gauge to 27 gauge, while the length can vary between 12-inch to 5 ⁄ 8-inch for injections using a syringe and needle. [ 3 ] : 722 For subcutaneous injections delivered using devices such as injector pens , the needle used may be as thin as 34 gauge (commonly 30–32 gauge), and as short as 3 ...

  7. Methylprednisolone acetate - Wikipedia

    en.wikipedia.org/wiki/Methylprednisolone_acetate

    [1] [4] [5] Methylprednisolone acetate was previously suspended with polyethylene glycol but is no longer formulated with this excipient due to concerns about possible toxicity. [ 6 ] [ 8 ] Depo methylprednisolone acetate is a depot injection and is absorbed slowly with a duration of weeks to months with a single intramuscular injection.

  8. Methylprednisolone suleptanate - Wikipedia

    en.wikipedia.org/wiki/Methylprednisolone_suleptanate

    Methylprednisolone suleptanate, sold under the brand names Medrosol and Promedrol, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically, the C21 suleptanate 21-(8-(methyl-(2-sulfoethyl)amino)-1,8-dioxooctanoate) ester of methylprednisolone. [1] [2] It acts as a prodrug of methylprednisolone. [3]

  9. Glucose clamp technique - Wikipedia

    en.wikipedia.org/wiki/Glucose_clamp_technique

    The hyperglycemic clamp, which requires maintaining a high blood sugar level by perfusion or infusion with glucose, is a way to quantify how fast beta-cells respond to glucose. The hyperinsulinemic clamp, which requires maintaining a high insulin level by perfusion or infusion with insulin, is a way to quantify how sensitive the tissue is to ...

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