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The dermatome is the dorsal portion of the paraxial mesoderm somite which gives rise to the skin . In the human embryo, it arises in the third week of embryogenesis . [ 2 ] It is formed when a dermomyotome (the remaining part of the somite left when the sclerotome migrates), splits to form the dermatome and the myotome. [ 2 ]
[4] [5] However, the segmentation clock model is highly evolutionarily conserved. [ 6 ] Intrinsic expression of "clock genes" must oscillate with a periodicity equal to the time necessary for one somite to form, for example 30 minutes in zebrafish, 90 minutes in chicks, and 100 minutes in snakes.
The notochord and the neural tube activate the protein SHH, which helps the somite to form its sclerotome. The cells of the sclerotome express the protein PAX1 that induces the cartilage and bone formation. The neural tube activates the protein WNT1 that expresses PAX 2 so the somite creates the myotome and dermatome.
Paraxial mesoderm, also known as presomitic or somitic mesoderm, is the area of mesoderm in the neurulating embryo that flanks and forms simultaneously with the neural tube. ...
The first seven somitomeres give rise to the striated muscles of the face, jaws, and throat. [2]The remaining somitomeres, likely driven by periodic expression of the hairy gene, begin expressing adhesion proteins such as N-cadherin and fibronectin, compact, and bud off forming somites.
As a matter of fact, these inhibitory chemicals expressed in the posterior sclerotome forms the basis of the segmentation pattern observed in the vertebrate nervous system. [12] In short, the segmental arrangement of the peripheral nervous system (PNS) seen in vertebrates derives from the division of the sclerotomes into anterior and posterior ...
The lateral plate mesoderm is the mesoderm that is found at the periphery of the embryo.It is to the side of the paraxial mesoderm, and further to the axial mesoderm.The lateral plate mesoderm is separated from the paraxial mesoderm by a narrow region of intermediate mesoderm.
The peripheral nervous system (PNS) is divided into the somatic nervous system, the autonomic nervous system, and the enteric nervous system.However, it is the somatic nervous system, responsible for body movement and the reception of external stimuli, which allows one to understand how cutaneous innervation is made possible by the action of specific sensory fibers located on the skin, as well ...