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Hepatitis B virus (HBV) is a partially double-stranded DNA virus, [1] a species of the genus Orthohepadnavirus and a member of the Hepadnaviridae family of viruses. [ 2 ] [ 3 ] This virus causes the disease hepatitis B .
Hepatitis B infection has been preventable by vaccination since 1982. [4] [12] As of 2022, the hepatitis B vaccine is between 98% and 100% effective in preventing infection. [1] The vaccine is administered in several doses; after an initial dose, two or three more vaccine doses are required at a later time for full effect. [1]
This controversy created public misgivings about hepatitis B vaccination, and hepatitis B vaccination in children remained low in several countries. A 2006 study concluded that evidence did not support an association between hepatitis B vaccination and sudden infant death syndrome , chronic fatigue syndrome , or multiple sclerosis. [ 52 ]
Hepatitis D is a defective virus that requires hepatitis B to replicate and is only found with hepatitis B co-infection. [17] In adults, hepatitis B infection is most commonly self-limiting, with less than 5% progressing to chronic state, and 20 to 30% of those chronically infected developing cirrhosis or liver cancer. [31]
Hepatitis B surface antigen: HBV: hepatitis B virus: HC: head circumference hemorrhagic colitis homocysteine HCA: Healthcare Associated, as in HCA-CDI HCAP: health care-associated (or acquired) pneumonia: HCC: hepatocellular carcinoma: HCF: Healthcare Facility HCFA: Healthcare Facility Associated, as in HCFA-CDI hCG: human chorionic ...
DTwP-HepB-Hib vaccine is a 5-in-1 combination vaccine with five individual vaccines conjugated into one. [1] It protects against diphtheria, tetanus, whooping cough, hepatitis B and Haemophilus influenzae type B, [1] which is generally used in middle- and low-income countries, where polio vaccine is given separately.
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The genome organisation of HBV; the genes overlap. ORF S, in green, encodes HBsAg. HBsAg under a transmission electron microscope: the protein self assembles into virus-like particles. HBsAg (also known as the Australia antigen) is the surface antigen of the hepatitis B virus (HBV). Its presence in blood indicates existing hepatitis B infection.
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