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Hepatitis B infections result in 500,000 to 1,200,000 deaths per year worldwide due to the complications of chronic hepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Hepatitis B is endemic in a number of (mainly South-East Asian) countries, making cirrhosis and hepatocellular carcinoma big killers.
Hepatitis B incidence rate in 2017. [107] Approximately 254 million people had chronic HBV infection as of 2022. Another 1.2 million cases of acute HBV infection also occurred that year. [108] Regional prevalences across the globe range from around 7.5% in Africa to 0.5% in the Americas. [19]
Hepatitis B: According to the World Health Organization, as of 2019 there are about 296 million people living with chronic hepatitis B, with 1.5 million new infections each year. In 2019, hepatitis B caused about 820,000 deaths, mostly from cirrhosis and hepatocellular carcinoma (primary liver cancer ). [ 23 ]
Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
Crude mortality rate refers to the number of deaths over a given period divided by the person-years lived by the population over that period. It is usually expressed in units of deaths per 1,000 individuals per year. The list is based on CIA World Factbook 2023 estimates, unless indicated otherwise.
The spread of hepatitis B virus in the western world occurs most often through sexual intercourse or needle sharing by intravenous drug users (IVDU). IVDU show the highest rate of HBV infection in Europe and North America. [74] There are also higher rates of hepatitis B infection among men who have sex with men (MSM).
Hepatitis D is a defective virus that requires hepatitis B to replicate and is only found with hepatitis B co-infection. [17] In adults, hepatitis B infection is most commonly self-limiting, with less than 5% progressing to chronic state, and 20 to 30% of those chronically infected developing cirrhosis or liver cancer. [ 31 ]
According to studies from the Institute for Health Metrics and Evaluation, from January 2020 to the end of September 2021 as a direct effect of COVID-19 pandemic, Japan registered at least 112,000 excess deaths with six times higher, [16] a reduction of about 2.6 years in the average life expectancy, a noticeable decrease in birth rates and a ...