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This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification. Chemical/generic names are listed first, with brand names in parentheses.
Note: the activities of the parent companies of many of the companies listed below are not restricted solely to the United Kingdom. For example, AstraZeneca and GlaxoSmithKline , although headquartered in the United Kingdom, have activities in numerous other countries, and Johnson & Johnson and Pfizer are both headquartered in the United States ...
Use of antidepressants during pregnancy may result in fetus abnormalities affecting functional development of the brain and behavior. [90] Studies have shown correlations between pregnant women treated with SNRIs and risk of hypertensive disorders, [91] preeclampsia, [92] miscarriage, [93] seizures in children, [94] and many other adverse affects.
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Warfarin (brand name Coumadin) is a commonly prescribed blood thinner both in the inpatient and outpatient hospital settings. In pregnant women, warfarin is contraindicated and should be avoided as it crosses the placental barrier. Additionally, warfarin is listed as Pregnancy Category D, which means it has a risk of harming the fetus. [37]
(4) See list of investigational antidepressants for an extensive list of modern investigational antidepressants (including discontinued agents). The earliest and most widely known scientific theory of antidepressant action is the monoamine hypothesis , which can be traced back to the 1950s and 1960s.
A new Canadian study suggests that women who take antidepressants during pregnancy may be more likely to give birth to children with autism.
Desvenlafaxine is a synthetic form of the isolated major active metabolite of venlafaxine, and is categorized as a serotonin-norepinephrine reuptake inhibitor (SNRI). When most normal metabolizers take venlafaxine, approximately 70% of the dose is metabolized into desvenlafaxine, so the effects of the two drugs are expected to be very similar. [18]
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