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Fructose malabsorption, formerly named dietary fructose intolerance (DFI), is a digestive disorder [1] in which absorption of fructose is impaired by deficient fructose carriers in the small intestine's enterocytes. This results in an increased concentration of fructose. Intolerance to fructose was first identified and reported in 1956. [2]
Fructose intolerance may refer to: Fructose malabsorption , a digestive disorder of the small intestine in which the fructose carrier in enterocytes is deficient Hereditary fructose intolerance , a hereditary condition caused by a deficiency of liver enzymes that metabolise fructose
Food intolerances can be classified according to their mechanism. Intolerance can result from the absence of specific chemicals or enzymes needed to digest a food substance, as in hereditary fructose intolerance. It may be a result of an abnormality in the body's ability to absorb nutrients, as occurs in fructose malabsorption.
After ingestion, fructose is converted to fructose-1-phosphate in the liver by fructokinase. Deficiencies of fructokinase cause essential fructosuria, a clinically benign condition characterized by the excretion of unmetabolized fructose in the urine. Fructose-1-phosphate is metabolized by aldolase B into dihydroxyacetone phosphate and ...
Lactose intolerance is found in most adults, except for specific geographic populations, notably those of European descent. [20] Many who benefit from a low FODMAP diet need not restrict fructose or lactose. It is possible to identify these two conditions with hydrogen and methane breath testing, thus eliminating the necessity for dietary ...
Due to high protein content, egg white allergy is more common than the reverse. [11] The majority of children with this allergy become tolerant by adulthood. [12] Fish: Respiratory reactions, Anaphylaxis, oral allergy syndrome, sometimes vomiting One of three allergies to seafood, not to be conflated with allergies to crustaceans and mollusks. [13]
Fructose can be bad for your health when consumed as part of high-fructose corn syrup in processed foods. Past studies have linked high-fructose corn syrup intake to many diseases, including cancer.
Fructose malabsorption or Dietary Fructose Intolerance is a dietary disability of the small intestine, where the amount of fructose carrier in enterocytes is deficient. [ 8 ] In humans the GLUT5 protein is encoded by the SLC2A5 gene .