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  2. Clindamycin - Wikipedia

    en.wikipedia.org/wiki/Clindamycin

    Clindamycin. Clindamycin is a lincosamide antibiotic medication used for the treatment of a number of bacterial infections, including osteomyelitis (bone) or joint infections, pelvic inflammatory disease, strep throat, pneumonia, acute otitis media (middle ear infections), and endocarditis. [ 5 ]

  3. Antimicrobial spectrum - Wikipedia

    en.wikipedia.org/wiki/Antimicrobial_spectrum

    Antimicrobial spectrum. A simplified diagram showing common disease-causing bacteria and the antibiotics which act against them. The antimicrobial spectrum of an antibiotic means the range of microorganisms it can kill or inhibit. Antibiotics can be divided into broad-spectrum antibiotics, extended-spectrum antibiotics and narrow-spectrum ...

  4. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    Wide range of infections; penicillin used for streptococcal infections, syphilis, and Lyme disease: Gastrointestinal upset and diarrhea; Allergy with serious anaphylactic reactions; Brain and kidney damage (rare) Same mode of action as other beta-lactam antibiotics: disrupt the synthesis of the peptidoglycan layer of bacterial cell walls ...

  5. Lincosamides - Wikipedia

    en.wikipedia.org/wiki/Lincosamides

    Lincosamides are often used clinically as an alternative antibiotic for patients who are allergic to penicillin. Of the lincosamides, clindamycin is most commonly used within the clinic due to its higher bioavailability, higher oral absorption and efficacy within the target organism spectrum. [ 23 ]

  6. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    β-Lactam antibiotics (beta-lactam antibiotics) are antibiotics that contain a β-lactam ring in their chemical structure. This includes penicillin derivatives (penams), cephalosporins and cephamycins (cephems), monobactams, carbapenems [1] and carbacephems. [2] Most β-lactam antibiotics work by inhibiting cell wall biosynthesis in the ...

  7. Lincomycin - Wikipedia

    en.wikipedia.org/wiki/Lincomycin

    Lincomycin. Lincomycin is a lincosamide antibiotic that comes from the actinomycete Streptomyces lincolnensis. [3] A related compound, clindamycin, is derived from lincomycin by using thionyl chloride to replace the 7-hydroxy group with a chlorine atom with inversion of chirality. [4] It was released for medical use in September 1964.

  8. Broad-spectrum antibiotic - Wikipedia

    en.wikipedia.org/wiki/Broad-spectrum_antibiotic

    A broad- spectrum antibiotic is an antibiotic that acts on the two major bacterial groups, Gram-positive and Gram-negative, [1] or any antibiotic that acts against a wide range of disease-causing bacteria. [2] These medications are used when a bacterial infection is suspected but the group of bacteria is unknown (also called empiric therapy) or ...

  9. Eagle effect - Wikipedia

    en.wikipedia.org/wiki/Eagle_effect

    The Eagle effect, Eagle phenomenon, or paradoxical zone phenomenon, named after Harry Eagle who first described it, originally referred to the paradoxically reduced antibacterial effect of penicillin at high doses, [1][2] though recent usage generally refers to the relative lack of efficacy of beta lactam antibacterial drugs on infections ...

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