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  2. Major depressive episode - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_episode

    Medication. Antidepressants. A major depressive episode (MDE) is a period characterized by symptoms of major depressive disorder. Those affected primarily exhibit a depressive mood for at least two weeks or more, and a loss of interest or pleasure in everyday activities. Other symptoms can include feelings of emptiness, hopelessness, anxiety ...

  3. Major depressive disorder - Wikipedia

    en.wikipedia.org/wiki/Major_depressive_disorder

    Major depressive disorder (MDD), also known as clinical depression, is a mental disorder [ 9 ] characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, [ 10 ] the term was adopted by the American ...

  4. Atypical depression - Wikipedia

    en.wikipedia.org/wiki/Atypical_depression

    The DSM-5 defines atypical depression as a subtype of major depressive disorder that presents with "atypical features", characterized by: Mood reactivity (i.e., mood brightens in response to actual or potential positive events) At least two of the following: Significant weight gain or increase in appetite (hyperphagia);

  5. Differential diagnoses of depression - Wikipedia

    en.wikipedia.org/wiki/Differential_diagnoses_of...

    Multiple sclerosis. Multiple sclerosis is a chronic demyelinating disease in which the myelin sheaths of cells in the brain and spinal cord are irreparably damaged. Symptoms of depression are very common in patients at all stages of the disease and may be exacerbated by medical treatments, notably interferon beta-1a.

  6. Mood disorder - Wikipedia

    en.wikipedia.org/wiki/Mood_disorder

    Depressive disorder (also known as depression) is a common mental disorder. It involves a depressed mood or loss of pleasure or interest in activities for long periods of time. Depression is different from regular mood changes and feelings about everyday life. It can affect all aspects of life.

  7. Depression (mood) - Wikipedia

    en.wikipedia.org/wiki/Depression_(mood)

    Emotions. v. t. e. Depression is a mental state of low mood and aversion to activity. [3] It affects about 3.5% of the global population, or about 280 million people of all ages (as of 2020). [4] Depression affects a person's thoughts, behavior, feelings, and sense of well-being. [5]

  8. Biology of depression - Wikipedia

    en.wikipedia.org/wiki/Biology_of_depression

    Biology of depression. Appearance. Scientific studies have found that different brain areas show altered activity in humans with major depressive disorder (MDD), [ 1 ] and this has encouraged advocates of various theories that seek to identify a biochemical origin of the disease, as opposed to theories that emphasize psychological or ...

  9. Mental disorder - Wikipedia

    en.wikipedia.org/wiki/Mental_disorder

    A mental disorder, also referred to as a mental illness, [ 6 ] a mental health condition, [ 7 ] or a psychiatric disability, [ 2 ] is a behavioral or mental pattern that causes significant distress or impairment of personal functioning. [ 8 ] A mental disorder is also characterized by a clinically significant disturbance in an individual's ...

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