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Apalutamide was first described in 2007, and was approved for the treatment of prostate cancer in February 2018. [8] [9] [10] [15] It is the first medication to be approved specifically for the treatment of non-metastatic castration-resistant prostate cancer. [2] [10] [9]
[19] 3α-Androstanediol is a potent positive allosteric modulator of the GABA A receptor, while 3β-androstanediol is a potent and selective agonist of the estrogen receptor (ER) subtype ERβ. [19] These metabolites may play important roles in the central effects of DHT and by extension testosterone, including their antidepressant , anxiolytic ...
A 2010 review found a 25% reduction in the risk of prostate cancer with 5α-reductase inhibitor. [33] A follow-up study of the Medicare claims of participants in a 10-year Prostate Cancer Prevention Trial suggests the reduction in prostate cancer is maintained even after discontinuation of treatment. [34]
Flutamide, sold under the brand name Eulexin among others, is a nonsteroidal antiandrogen (NSAA) which is used primarily to treat prostate cancer. [9] [10] It is also used in the treatment of androgen-dependent conditions like acne, excessive hair growth, and high androgen levels in women. [11]
Benign prostatic hyperplasia (BPH), also called prostate enlargement, is a noncancerous increase in size of the prostate gland. [1] Symptoms may include frequent urination , trouble starting to urinate, weak stream, inability to urinate , or loss of bladder control . [ 1 ]
In 2012, investigators seemingly brought long-awaited closure to one of the nation's oldest and most high-profile kidnapping cases, solving it after more than 50 years.
Smartwatches are a hot-ticket gift over the holidays, but a new study might have you rethink how you strap the device to your wrist in the future.
Testosterone is the primary male sex hormone and androgen in males. [3] In humans, testosterone plays a key role in the development of male reproductive tissues such as testicles and prostate, as well as promoting secondary sexual characteristics such as increased muscle and bone mass, and the growth of body hair.
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