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Symptoms: Increased fat deposits under the skin in the legs, increased extracellular fluid, inflammation, [1] easy bruising, pain [2] Causes: Unknown [2] Risk factors: Family member with the condition [3] Differential diagnosis: Lipohypertrophy, chronic venous insufficiency, lymphedema [2] Treatment
Lipodystrophy syndromes are a group of genetic or acquired disorders in which the body is unable to produce and maintain healthy fat tissue. [ 1 ] [ 2 ] The medical condition is characterized by abnormal or degenerative conditions of the body's adipose tissue .
Pain: can be constant or just when the area is touched. Loss of function: difficulty moving a joint, an infection in the lungs, immobility. However, chronic inflammation isn’t always easily ...
Common adverse effects include diarrhea, nausea, and abdominal pain. [16] It has a small risk of causing low blood sugar. [16] High blood lactic acid level is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems. [23] [24] Metformin is a biguanide anti-hyperglycemic agent. [16]
Some people take metformin once, twice, or even three times a day, depending on the type of metformin (tablet or liquid) and how many milligrams they’re prescribed. Again, aim to take it at the ...
Another small study on people without diabetes who were overweight or had obesity found that those taking metformin lost between 5.6 and 6.5 percent of their body weight. In contrast, the control ...
Acquired generalized lipodystrophy (AGL), also known as Lawrence syndrome [1] and Lawrence–Seip syndrome, [1] is a rare skin condition that appears during childhood or adolescence, characterized by fat loss affecting large areas of the body, particularly the face, arms, and legs.
Sclerosing mesenteritis may present with no or nearly no signs or symptoms, but many people have chronic and severe pain in the abdomen as the most common chief complaint. Other people have chronic problems with bowel movements, resulting in diarrhea, bloating, gas, and cramping which can range from severe to mild. [4] [5]