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Leishmania then invades human macrophages and replicates intracellularly. A raised, red lesion develops at the site of the bite (often weeks or sometimes years afterwards). The lesion then ulcerates and may become secondarily infected with bacteria. In many species (for example, L. major) the lesion often spontaneously heals with atrophic scarring.
Diffuse cutaneous leishmaniasis produces widespread skin lesions which resemble leprosy, and may not heal on their own. [3] Mucocutaneous leishmaniasis causes both skin and mucosal ulcers with damage primarily of the nose and mouth. [2] [3] Visceral leishmaniasis or kala-azar ('black fever') is the most serious form and is generally fatal if ...
PKDL lesions on hand. Post-kala-azar dermal leishmaniasis (PKDL) is a complication of visceral leishmaniasis (VL); it is characterised by a macular, maculopapular, and nodular rash in a patient who has recovered from VL and who is otherwise well. The rash usually starts around the mouth from where it spreads to other parts of the body depending ...
26 pictures of skin rashes to help you identify your skin rash. ... Molluscum is a rash caused by the poxvirus and leads to small groups of bumps on the skin, says Dr. Jacobs. “The lesions are ...
What it looks like: Purplish lesions on the inner arms, legs, wrists, or ankles can signify lichen planus, a skin rash triggered by an overreaction of the immune system.
This condition manifests first as small, measle-like skin lesions on the face, which gradually increase in size and spread over the body. Eventually the lesions may coalesce to form disfiguring, swollen structures resembling leprosy , and occasionally causing blindness if they spread to the eyes.
The superficial layers of the skin are naturally acidic (pH 4–4.5) due to lactic acid in sweat and produced by skin bacteria. [31] At this pH mutualistic flora such as Staphylococci , Micrococci , Corynebacterium and Propionibacteria grow but not transient bacteria such as Gram-negative bacteria like Escherichia and Pseudomonas or Gram ...
List of human leukocyte antigen alleles associated with cutaneous conditions; List of immunofluorescence findings for autoimmune bullous conditions; List of inclusion bodies that aid in diagnosis of cutaneous conditions; List of keratins expressed in the human integumentary system; List of radiographic findings associated with cutaneous conditions