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The anticonvulsant drug, lamotrigine, has been associated with a decrease in white blood cell count. [2] The FDA monograph for metronidazole states that this medication can also cause leukopenia, and the prescriber information suggests a complete blood count, including differential cell count, before and after, in particular, high-dose therapy. [3]
An excess of white blood cells is usually due to infection or inflammation. Less commonly, a high white blood cell count could indicate certain blood cancers or bone marrow disorders. The number of leukocytes in the blood is often an indicator of disease, and thus the white blood cell count is an important subset of the complete blood count.
Growth factors, synthetic versions of substances involved in stimulating red and white blood cell production, such as G-CSF and GM-CSF. People with leukopenia are advised to avoid contact with people who are ill, monitor closely for signs of infection, and take antibiotics when appropriate.
Agranulocytosis, also known as agranulosis or granulopenia, is an acute condition involving a severe and dangerous lowered white blood cell count (leukopenia, most commonly of neutrophils) and thus causing neutropenia in the circulating blood. [1] It is a severe lack of one major class of infection-fighting white
The white blood cell differential is a common blood test that is often ordered alongside a complete blood count.The test may be performed as part of a routine medical examination; to investigate certain symptoms, particularly those suggestive of infection or hematological disorders; [5] [6] or to monitor existing conditions, such as blood disorders and inflammatory diseases.
A complete blood count (CBC), also known as a full blood count (FBC), is a set of medical laboratory tests that provide information about the cells in a person's blood.The CBC indicates the counts of white blood cells, red blood cells and platelets, the concentration of hemoglobin, and the hematocrit (the volume percentage of red blood cells).
Morning pseudoneutropenia is thought to be due to diurnal variation in the amount of circulating white blood cells and changes in the levels of hematopoietic cytokines and granulocyte colony stimulating factor (GCSF). [1] Antipsychotics may amplify the natural variation in these hematopoietic factors. [citation needed]
Leukapheresis (/ ˌ l u ˈ k ʌ f ɜːr iː s ɪ s / ⓘ) is a laboratory procedure in which white blood cells are separated from a sample of blood. It is a specific type of apheresis, the more general term for separating out one particular constituent of blood and returning the remainder to the circulation.