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The basic structure of a CRAM file is a series of containers, the first of which holds a compressed copy of the SAM header. Subsequent containers consist of a container Compression Header followed by a series of slices which in turn hold the alignment records themselves, formatted as a series of blocks.
The feature type name, like "gene" or "exon". In a well structured GFF file, all the children features always follow their parents in a single block (so all exons of a transcript are put after their parent "transcript" feature line and before any other parent transcript line).
Read the specified unsorted_in.bam as input, sort it in blocks up to 5 million k (5 Gb) [units verification needed] and write output to a series of bam files named sorted_out.0000.bam, sorted_out.0001.bam, etc., where all bam 0 reads come before any bam 1 read, etc. [verification needed] index samtools index sorted.bam
The main idea of BLAST is that there are often High-scoring Segment Pairs (HSP) contained in a statistically significant alignment. BLAST searches for high scoring sequence alignments between the query sequence and the existing sequences in the database using a heuristic approach that approximates the Smith-Waterman algorithm.
Locally Optimal Block Preconditioned Conjugate Gradient (LOBPCG) is a matrix-free method for finding the largest (or smallest) eigenvalues and the corresponding eigenvectors of a symmetric generalized eigenvalue problem
The software development platform GitHub has been the target of censorship from governments using methods ranging from local Internet service provider blocks, intermediary blocking using methods such as DNS hijacking and man-in-the-middle attacks, and denial-of-service attacks on its servers from countries including China, India, Iraq, Russia, and Turkey.
The workflow consists of blocks such as data readers, blocks executing embedded tools and algorithms, and data writers. Blocks can be created with command line tools or a script. A set of sample workflows is available in the Workflow Designer, to annotate sequences, convert data formats, analyze NGS data, etc.
The idea for the BLAST product belongs to Paul Charbonnet, Jr., a former Data General salesman. Its original version was designed and implemented for the Data General line of Nova minicomputers [17] [18] by G. W. Smith, a former BorgWarner Research Center systems engineer who, having developed a basic "ack-nak" protocol for the aforesaid telemetry application, now created an entirely new ...