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Staphylococcus lugdunensis has been associated with a wide variety of infections, including cardiovascular infections (severe native and prosthetic valve endocarditis, myocarditis, and infected myxoma), empyema, osteomyelitis and prosthetic/native joints infections, skin and soft-tissue infections (furuncles, cellulitis, and abscesses), central nervous infections, peritonitis, endocephalitis ...
Lugdunin is an investigational antibiotic, classified as a thiazolidine-containing cyclic peptide.It was isolated in 2016 after Staphylococcus lugdunensis was identified as the species of bacteria from the human nose that suppressed growth of species of disease-causing bacteria in that part of the human microbiome.
A staphylococcal infection or staph infection is an infection caused by members of the Staphylococcus genus of bacteria. These bacteria commonly inhabit the skin and nose where they are innocuous, but may enter the body through cuts or abrasions which may be nearly invisible.
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Staphylococcus species are facultative anaerobes (capable of growth both aerobically and anaerobically). [15] All species grow in the presence of bile salts. All strains of Staphylococcus aureus were once thought to be coagulase-positive, but this has since been disproven. [16] [17] [18] Growth can also occur in a 6.5% NaCl solution. [15]
Staphylococcus lugdunensis is an example of a commensal bacteria with closed pan-genome. [25] ... between 80 and 90% of gene models were found as core genes. The ...
In the laboratory, it is used to distinguish between different types of Staphylococcus isolates. Importantly, S. aureus is generally coagulase-positive, meaning that a positive coagulase test would indicate the presence of S. aureus or any of the other 11 coagulase-positive Staphylococci. [1]
An MSA plate with Micrococcus sp. (1), Staphylococcus epidermidis (2) and S. aureus colonies (3). Mannitol salt agar or MSA is a commonly used selective and differential growth medium in microbiology. It encourages the growth of a group of certain bacteria while inhibiting the growth of others. [1]