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One Cochrane review supports its efficacy in preventing the spread of pertussis. [41] Shigellosis: Yes: Yes: No: Generally accepted treatment for shigellosis. [42] A Cochrane review found that while it is an effective treatment for shigellosis it also produces more significant adverse effects than other antibiotic drugs. [43] Staphylococcus ...
Drug fever; Periarteritis nodosa; Hepatic necrosis; Pancreatitis; Myelosuppression; Haemolysis [a] Stevens–Johnson syndrome [b] Drug reaction with eosinophilia and systemic symptoms; Toxic epidermal necrolysis [c] Ataxia [d] Clostridioides difficile colitis; Aseptic meningitis [e] Pseudomembranous colitis; Interstitial nephritis; Fulminant ...
Its Tmax (or time to reach maximum drug concentration in plasma) occurs 1 to 4 hours after oral administration. The mean serum half-life of sulfamethoxazole is 10 hours. [8] However, the half-life of the drug noticeably increases in people with creatinine clearance rates equal to or less than 30 mL/minute.
Trimethoprim (TMP) is an antibiotic used mainly in the treatment of bladder infections. [1] Other uses include for middle ear infections and travelers' diarrhea. [1] With sulfamethoxazole or dapsone it may be used for Pneumocystis pneumonia in people with HIV/AIDS. [1] [2] It is taken orally (swallowed by mouth). [1]
Treatment of Clostridioides (formerly Clostridium) difficile infection. [8] May be more narrow-spectrum than vancomycin, resulting in less bowel microbiota alteration. [9] Nausea (11%), vomiting, and abdominal pain. [10] Bactericidal in susceptible organisms such as C. difficile by inhibiting RNA polymerase, thereby inhibiting protein synthesis ...
(formerly known as TP-434) received FDA approval on August 27, 2018, for treatment of complicated intra-abdominal infections. [54] Sarecycline: 16+ hours (long) (formerly known as WC 3035) received FDA approval on October 1, 2018, for treatment of moderate to severe acne vulgaris. [55] Sarecycline is a narrow-spectrum antibiotic. [56] [57 ...
Urinary anti-infective agent, also known as urinary antiseptic, is medication that can eliminate microorganisms causing urinary tract infection (UTI). UTI can be categorized into two primary types: cystitis , which refers to lower urinary tract or bladder infection, and pyelonephritis , which indicates upper urinary tract or kidney infection. [ 1 ]
The 2023 updated Johnson & Johnson Consumer Inc. label for their product discloses three different antibiotics: bacitracin zinc 400 units, neomycin sulfate 3.5 mg, and polymyxin B sulfate 5,000 units, in a relatively low-molecular-weight base of petroleum jelly, cottonseed oil, olive oil, and cocoa butter, and with sodium pyruvate and ...
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