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In the elderly, vitamin B 12 deficiency has been associated with the development of macular degeneration, and the risk of frailty. [90] Macular degeneration is the leading cause of severe, irreversible vision loss in older adults.
Ish-Shalom et al. [69] performed a study in elderly women to compare the efficacy and safety of a daily dose of 1500 IU to a weekly dose of 10 500 IU and to a dose of 45 000 IU given every 28 days for two months. They concluded that supplementation with vitamin D can be equally achieved with daily, weekly, or monthly dosing frequencies.
Malabsorption is a state arising from abnormality in absorption of food nutrients across the gastrointestinal (GI) tract. Impairment can be of single or multiple nutrients depending on the abnormality.
Pernicious anemia is a disease where not enough red blood cells are produced due to a deficiency of vitamin B 12. [5] Those affected often have a gradual onset. [5] The most common initial symptoms are feeling tired and weak. [4]
Vitamin deficiency is the condition of a long-term lack of a vitamin.When caused by not enough vitamin intake it is classified as a primary deficiency, whereas when due to an underlying disorder such as malabsorption it is called a secondary deficiency.
Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. [11] [12] Specifically, it is a deficiency, excess, or imbalance of energy, protein and other nutrients which adversely affects the body's tissues and form.
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Malabsorption is the inability to absorb food fully, mostly from disorders in the small bowel, but also due to maldigestion from diseases of the pancreas. Causes include: [ citation needed ] enzyme deficiencies or mucosal abnormality , as in food allergy and food intolerance , e.g. celiac disease (gluten intolerance), lactose intolerance ...