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An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
There are no clinical guidelines outlining the use and implementation of opioid rotation. However, this strategy is commonly used for these various situations: pain not controlled by current opioid, pain controlled but in the presence of intolerable adverse events, pain not controlled despite rapid increase in opioid dose, switching to utilize different alternative routes of administration, or ...
Opioid dose conversions may be necessary when switching medications given the differing pharmacodynamics between opioids. Generally, parenteral (IV or IM) morphine is used as the standard for converting between opiates to achieve equivalent analgesic effects.
The intravenous dose causing 50% of opioid-naive experimental subjects to die (LD 50) is "3 mg/kg in rats, 1 mg/kg in cats, 14 mg/kg in dogs, and 0.03 mg/kg in monkeys." [ 98 ] The LD 50 in mice has been given as 6.9 mg/kg by intravenous administration, 17.5 mg/kg intraperitoneally, 27.8 mg/kg by oral administration. [ 99 ]
Drug 9050 opiate Codeine [2] 9334 opiate Dihydroetorphine [3] 9190 opiate Ethylmorphine [2] 9059 opiate Etorphine hydrochloride [4] 9640 opiate Granulated opium [2] 9193 opiate Hydrocodone [2] 9150 opiate Hydromorphone [2] 9260 opiate Metopon [2] 9300 opiate Morphine [2] 9668 opiate Noroxymorphone [5] 9610 opiate Opium extracts [2] 9620 opiate ...
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In the Netherlands, morphine is classified as a List 1 drug under the Opium Law. In New Zealand, morphine is classified as a Class B drug under the Misuse of Drugs Act 1975. [153] In the United Kingdom, morphine is listed as a Class A drug under the Misuse of Drugs Act 1971 and a Schedule 2 Controlled Drug under the Misuse of Drugs Regulations ...
Maples recovered from the infection but was diminished, her family says. She died Feb. 4, 2012, after choking to death from a mucus obstruction that clogged her airway, an autopsy concluded. Maples' family believes the Vitas’ drug regimen weakened her, and the health crisis she suffered while under the hospice's care damaged her already frail ...