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CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic cells. [1] It was first developed by Stanley Qi and colleagues in the laboratories of Wendell Lim , Adam Arkin, Jonathan Weissman , and Jennifer Doudna . [ 2 ]
CRISPR activation (CRISPRa) is a gene regulation technique that utilizes an engineered form of the CRISPR-Cas9 system to enhance the expression of specific genes without altering the underlying DNA sequence.
Apart from knock-out there are also knock-down (CRISPRi) and activation (CRISPRa) libraries, which use the ability of proteolytically deactivated Cas9-fusion proteins (dCas9) to bind target DNA, which means that a gene of interest is not cut but is over-expressed or repressed. It made CRISPR/Cas9 system even more interesting in gene editing.
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Dictionary of the Bible: 1965 John L. McKenzie, SJ [clarification needed] The New Westminster Dictionary of the Bible: 1970 Henry Snyder Gehman LDS Bible Dictionary: 1979 Harper's Bible Dictionary: 1985 Paul J. Achtemeier: The Eerdmans Bible Dictionary: 1987 Allen C. Myers Anchor Bible Dictionary: 1992 Oxford Dictionary of the Bible: 1996 W. R ...
Oxford spelling (also Oxford English Dictionary spelling, Oxford style, or Oxford English spelling) is a spelling standard, named after its use by the Oxford University Press, that prescribes the use of British spelling in combination with the suffix -ize in words like realize and organization instead of -ise endings.
CRISPR RNA or crRNA is a RNA transcript from the CRISPR locus. [1] CRISPR-Cas (clustered, regularly interspaced short palindromic repeats - CRISPR associated systems) is an adaptive immune system found in bacteria and archaea to protect against mobile genetic elements, like viruses, plasmids, and transposons. [2]
The dictionary is not based on the Oxford English Dictionary (OED) – it is a separate dictionary which strives to represent faithfully the current usage of English words. The Revised Second Edition contains 355,000 words, phrases, and definitions, including biographical references and thousands of encyclopaedic entries.