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CRISPR interference (CRISPRi) is a genetic perturbation technique that allows for sequence-specific repression of gene expression in prokaryotic and eukaryotic cells. [1] It was first developed by Stanley Qi and colleagues in the laboratories of Wendell Lim , Adam Arkin, Jonathan Weissman , and Jennifer Doudna . [ 2 ]
Apart from knock-out there are also knock-down (CRISPRi) and activation (CRISPRa) libraries, which use the ability of proteolytically deactivated Cas9-fusion proteins (dCas9) to bind target DNA, which means that a gene of interest is not cut but is over-expressed or repressed. It made CRISPR/Cas9 system even more interesting in gene editing.
This is a comparison of English dictionaries, which are dictionaries about the language of English.The dictionaries listed here are categorized into "full-size" dictionaries (which extensively cover the language, and are targeted to native speakers), "collegiate" (which are smaller, and often contain other biographical or geographical information useful to college students), and "learner's ...
The dictionary is not based on the Oxford English Dictionary (OED) – it is a separate dictionary which strives to represent faithfully the current usage of English words. The Revised Second Edition contains 355,000 words, phrases, and definitions, including biographical references and thousands of encyclopaedic entries.
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The Oxford English Dictionary (OED) is the principal historical dictionary of the English language, published by Oxford University Press (OUP), a University of Oxford publishing house. The dictionary, which published its first edition in 1884, traces the historical development of the English language, providing a comprehensive resource to ...
The publisher of the Oxford English Dictionary added that the word can also be used as a verb, in the phrase “rizz up,” meaning to attract or chat up a person.
The other contenders for the title: Eight words were selected (and their meanings explained) for a public vote before Oxford’s linguists chose the winner from a list of four finalists ...