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HIV is the cause of the spectrum of disease known as HIV/AIDS. HIV is a retrovirus that primarily infects components of the human immune system such as CD4 + T cells, macrophages and dendritic cells. It directly and indirectly destroys CD4 + T cells. [88] HIV is a member of the genus Lentivirus, [89] part of the family Retroviridae. [90]
Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is the virus that was initially discovered and termed both lymphadenopathy associated virus (LAV) and human T-lymphotropic virus 3 (HTLV-III). HIV-1 is more virulent and more infective than HIV-2, [20] and is the cause of the majority of HIV infections globally. The lower ...
Another cause is the breakdown of the immune surveillance system of the mucosal barrier caused by the depletion of mucosal CD4 + T cells during the acute phase of disease. [ 7 ] This results in the systemic exposure of the immune system to microbial components of the gut’s normal flora, which in a healthy person is kept in check by the ...
HIV/AIDS denialism is the belief, despite conclusive evidence to the contrary, that the human immunodeficiency virus (HIV) does not cause acquired immune deficiency syndrome (AIDS). [ 1 ] [ 2 ] [ 3 ] Some of its proponents reject the existence of HIV, while others accept that HIV exists but argue that it is a harmless passenger virus and not ...
HIV is a major cause of cardiomyopathy (problems with the heart muscle that reduce the efficiency with which the heart pumps blood). The most common type of HIV induced cardiomyopathy is dilated cardiomyopathy also known as eccentric ventricular hypertrophy which leads to impaired contraction of the ventricles due to volume overload.
HIV/AIDS affects economic growth by reducing the availability of human capital. [1] Without proper prevention, nutrition, health care and medicine that is available in developing countries, large numbers of people are developing AIDS. People living with HIV/AIDS will not only be unable to work, but will also require significant medical care.
The declaration was drafted in response to HIV/AIDS denialism, and particularly to address South African president Thabo Mbeki's support for AIDS denialists. [2] It was written several weeks before the 2000 International AIDS Conference , held in Durban, South Africa from July 9 to 14, 2000, and was published in the journal Nature to coincide ...
In some cases, diarrhea may be a side effect of several drugs used to treat HIV, or it may simply accompany HIV infection, particularly during primary HIV infection. It may also be a side effect of antibiotics used to treat bacterial causes of diarrhea (common for Clostridioides difficile). In the later stages of HIV infection, diarrhea is ...