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Pain, swelling, bluish discoloration Paroxysmal hand hematoma , also known as Achenbach syndrome , is a skin condition characterized by spontaneous focal hemorrhage into the palm or the volar surface of a finger, which results in transitory localized pain, followed by rapid swelling and localized blueish discoloration .
Hunan hand syndrome (also known as "chili burn" [1]) is a temporary, but very painful, cutaneous condition that commonly afflicts those who handle, prepare, or cook with fresh or roasted chili peppers. [1] It was first described in an eponymous case report in The New England Journal of Medicine in 1981. [2]
Chemotherapy-induced acral erythema, also known as palmar-plantar erythrodysesthesia or hand-foot syndrome is reddening, swelling, numbness and desquamation (skin sloughing or peeling) on palms of the hands and soles of the feet (and, occasionally, on the knees, elbows, and elsewhere) that can occur after chemotherapy in patients with cancer.
A person with idiopathic carpal tunnel syndrome will not have any sensory loss over the thenar eminence (bulge of muscles in the palm of hand and at the base of the thumb). This is because the palmar branch of the median nerve, which innervates that area of the palm, separates from the median nerve and passes over the carpal tunnel. [39]
Patients may experience numbness, tingling, altered touch sensation, gait and balance disturbances, burning pain, thermal allodynia or hyperalgesia, impaired vibration sense, extreme temperature sensitivity, paresthesia, and/or dysesthesia as part of sensory damage. [3] On the other hand, motor symptoms are less frequently seen as sensory symptoms.
Late-onset GM2 gangliosidosis may also present as burning dysesthesia. [6] Chemotherapy-induced peripheral neuropathy is a progressive, enduring and often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs caused by some chemotherapy agents. [7]
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Besides peripheral neuropathy (presenting as paresthesia or itching, burning or pain) and discoloration, swelling and desquamation may occur. Since mercury blocks the degradation pathway of catecholamines, epinephrine excess causes profuse sweating (), tachycardia, salivation and elevated blood pressure.