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Equivalent dose is a dose quantity H representing the stochastic health effects of low levels of ionizing radiation on the human body which represents the probability ...
[2] [5] DOHx has shown the highest affinity for the serotonin 5-HT 2A and 5-HT 2C receptors of any other assessed DOx drug in multiple studies. [2] [3] [6] [5] In one study, its affinities for the human serotonin 5-HT 2 receptors were 0.1 nM for the 5-HT 2A receptor, 30 nM for the 5-HT 2B receptor, and 0.7 nM for 5-HT 2C receptor.
[1] [2] It was estimated that equivalent effects would be expected with (S)-MDMA 100 mg, MDMA 125 mg, and (R)-MDMA 300 mg. [1] [2] The findings of the study were overall regarded as not supporting the hypothesis that (R)-MDMA would produce equivalent therapeutic effects as (S)-MDMA or MDMA whilst reducing safety concerns.
CDE is defined by the United States Nuclear Regulatory Commission in Title 10, Section 20.1003, of the Code of Federal Regulations (10 CFR 20.1003), such that "The Committed dose equivalent, CDE (H T,50) is the dose to some specific organ or tissue of reference (T) that will be received from an intake of radioactive material by an individual during the 50-year period following the intake".
The drug's EC 50 Tooltip half-maximal effective concentration for activation of the serotonin 5-HT 2A receptor was 1.7 to 8.1 nM depending on the intracellular signaling cascade, while its E max Tooltip maximal efficacy was 99%. [10] At the serotonin 5-HT 2B receptor, its EC 50 was 68 nM (8- to 40-fold lower than for 5-HT 2A) and its E max was ...
0.5–5 mg/day Various: Estrogen: SC implant: 50–200 mg every 6–24 mos Estradiol valerate: Progynova: Estrogen: Oral: 2–10 mg/day Progynova: Estrogen: Sublingual: 1–8 mg/day Delestrogen [c] Estrogen: IM, SC: 2–10 mg/wk or 5–20 mg every 2 wks Estradiol cypionate: Depo-Estradiol: Estrogen: IM, SC: 2–10 mg/wk or 5–20 mg every 2 wks ...
An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]
Estrogen dosages for menopausal hormone therapy; Route/form Estrogen Low Standard High Oral: Estradiol: 0.5–1 mg/day: 1–2 mg/day: 2–4 mg/day Estradiol valerate: 0.5–1 mg/day: 1–2 mg/day