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Nonbenzodiazepine pharmacodynamics are similar in mechanism of action to benzodiazepine drugs, acting as GABA A receptor positive allosteric modulators of the benzodiazepine site, and therefore exhibit similar benefits, side effects, and risks.
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Zolpidem is a nonbenzodiazepine, or Z-drug, which acts as a sedative and hypnotic. [11] [20] Zolpidem is a GABA A receptor agonist of the imidazopyridine class. [11] It works by increasing GABA effects in the central nervous system by binding to GABA A receptors at the same location as benzodiazepines. [11] It generally has a half-life of two ...
Zopiclone, sold under the brand name Imovane among others, is a nonbenzodiazepine, specifically a cyclopyrrolone, used to treat difficulty sleeping.Zopiclone is molecularly distinct from benzodiazepine drugs and is classed as a cyclopyrrolone.
Saripidem is a sedative and anxiolytic drug in the imidazopyridine family, which is related to the better known drugs zolpidem and alpidem.. Saripidem has a similar pharmacological profile to the benzodiazepine family of drugs including sedative and anxiolytic properties, but its chemical structure is quite different from that of the benzodiazepine drugs, and saripidem is described as a ...
Onset of action: 10 to 30 minutes [6] Elimination half-life: 1 hr [4] Duration of action: ... It is a nonbenzodiazepine or Z-drug of the pyrazolopyrimidine class. [10]
Seppala also sent a team to study other clinics around the country. His staff went to facilities in Oregon and Missouri that were offering a mix of medically assisted treatments and 12-step. The team came back optimistic. “They saw in action how this could actually work,” Seppala said.
In terms of the mechanism of action of benzodiazepines, their similarities are too great to separate them into individual categories such as anxiolytic or hypnotic. For example, a hypnotic administered in low doses produces anxiety-relieving effects, whereas a benzodiazepine marketed as an anti-anxiety drug at higher doses induces sleep. [175]
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related to: nonbenzodiazepine action- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261