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Leptospirosis is a blood infection caused by the bacteria Leptospira [8] that can infect humans, dogs, rodents and many other wild and domesticated animals. [8] Signs and symptoms can range from none to mild (headaches, muscle pains, and fevers) to severe (bleeding in the lungs or meningitis). [5]
The reaction is also seen in the other diseases caused by spirochetes: Lyme disease, relapsing fever, and leptospirosis. [4] There have been case reports of the Jarisch–Herxheimer reaction accompanying treatment of other infections, including Q fever, bartonellosis, brucellosis, trichinellosis, and African trypanosomiasis. [3]
It is also used for malaria treatment and prophylaxis, as well as treating elephantitis filariasis. [10] Tetracyclines remain the treatment of choice for infections caused by chlamydia ( trachoma , psittacosis , salpingitis , urethritis and L. venereum infection ), Rickettsia ( typhus , Rocky Mountain spotted fever ), brucellosis and ...
Officials call the treatment doxy PEP, short for doxycycline postexposure prophylaxis. Doctors can write a prescription for one dose of 200 milligrams of doxycycline to be taken within three days ...
Doxycycline is less likely than other antibiotic drugs to cause Clostridioides difficile colitis. [75] An erythematous rash in sun-exposed parts of the body has been reported to occur in 7.3–21.2% of persons taking doxycycline for malaria prophylaxis. One study examined the tolerability of various malaria prophylactic regimens and found ...
Doxycycline is a class of medications typically used to treat bacterial STIs after someone has been infected — a method called post-exposure prophylaxis. However, recent research suggests that ...
Leptospira noguchii is another pathogenic bacteria that causes Leptospirosis. Leptospirosis can be transferred in a multitude of ways. Leptospirosis can transfer from animals to humans , humans to humans, or animals to animals via intake of contaminated body fluids, such as urine and blood. [7]
Leptospirosis is treated in humans by the antibiotics penicillin and doxycycline. [7] [8] L. interrogans has many properties that ensure its optimal survival in specific conditions, including two periplasmic flagella for movement and mobility. These flagella enable L. interrogans to more easily access and infect both human and mammalian tissues ...
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