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Leukopenia (from Greek λευκός (leukos) 'white' and πενία (penia) 'deficiency') is a decrease in the number of leukocytes (WBC). Found in the blood, they are the white blood cells, and are the body's primary defense against an infection. Thus the condition of leukopenia places individuals at increased risk of infection.
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The name "white blood cell" derives from the physical appearance of a blood sample after centrifugation.White cells are found in the buffy coat, a thin, typically white layer of nucleated cells between the sedimented red blood cells and the blood plasma.
Leukopenia – a deficiency of white blood cells, or leukocytes [1] Neutropenia – a type of leukopenia, with a specific deficiency in neutrophils [2] Thrombocytopenia – a deficiency of platelets; Pancytopenia – when all three types of blood cells; red blood cells, white blood cells, and platelets, are all deficient.
However, "-osis" is commonly used in blood disorders to imply cell proliferation (such as in "leukocytosis"), while "-penia" to imply reduced cell numbers (as in "leukopenia"); for these reasons, granulocytopenia is a more etymologically consistent term, and as such, is sometimes preferred to "agranulocytosis" (which can be misinterpreted as ...
The condition of having too few white blood cells is leukopenia, while having too many is leukocytosis. There are individual terms for the lack or overabundance of specific types of white blood cells. The number of white blood cells in circulation is commonly increased in the incidence of infection. [5]
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People with hairy cell leukemia who are symptom-free typically do not receive immediate treatment. Treatment is generally considered necessary when the person shows signs and symptoms such as low blood cell counts (e.g., infection-fighting neutrophil count below 1.0 K/μL), frequent infections, unexplained bruises, anemia, or fatigue that is ...