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When lactose intolerance is due to secondary lactase deficiency, treatment of the underlying disease may allow lactase activity to return to normal levels. [6] In people with celiac disease, lactose intolerance normally reverts or improves several months after starting a gluten-free diet , but temporary dietary restriction of lactose may be needed.
The subject of "food intolerance", including gluten sensitivity and elimination diets, was discussed in 1976. [51] Patients with symptoms including abdominal pain and diarrhea, which improved on gluten withdrawal, and who did not have celiac disease were initially described in 1976 and 1978 with the first series in 1980.
In 2011, Ritter Pharmaceuticals ceased sales of Lactagen, and other dietary supplements, in order to pursue FDA approval for a treatment for lactose intolerance. [1] Symptoms said to be relieved by Lactagen include bloating, gas, diarrhea, and abdominal cramping which are associated with the symptoms of lactose intolerance. [2]
[1] [11] The prevalence varies according to country (from 1.1% to 45.0%) and criteria used to define IBS; however the average global prevalence is 11.2%. [12] It is more common in South America and less common in Southeast Asia. [7] In the Western world, it is twice as common in women as men and typically occurs before age 45. [1]
Lactose intolerance may be present due to the decreased bowel surface and reduced production of lactase but typically resolves once the condition is treated. [ citation needed ] Alternative causes of this tissue damage have been proposed and involve the release of interleukin 15 and activation of the innate immune system by a shorter gluten ...
A T. aesitivum storage globulin, Glb-1 (locus), was identified that is similar to the hypersensitizing peanut protein Ara h 1 and other known plant hypersensitizing proteins. Antibodies to this protein correlated with levels of lymphocyte infiltration into Islet regions of the pancreas. [52] Gastrointestinal viruses may play a role. [53] [54 ...
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These gases are the cause of abdominal pain and other symptoms. [38] [41] Lactose intolerance does not cause damage to the gastrointestinal tract. [42] There are four types: primary, secondary, developmental and congenital. [43] Primary lactose intolerance is caused by decreasing levels of lactase brought on by age. [43]
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