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  2. Loperamide - Wikipedia

    en.wikipedia.org/wiki/Loperamide

    Loperamide, sold under the brand name Imodium, among others, [1] is a medication of the opioid receptor agonist class used to decrease the frequency of diarrhea. [5] [4] It is often used for this purpose in irritable bowel syndrome, inflammatory bowel disease, short bowel syndrome, [4] Crohn's disease, and ulcerative colitis. [5]

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  4. Antimotility agent - Wikipedia

    en.wikipedia.org/wiki/Antimotility_agent

    Antimotility agents are drugs used to alleviate the symptoms of diarrhea. These include loperamide (Imodium), bismuth subsalicylate (Pepto-Bismol), [1] diphenoxylate with atropine (Lomotil), and opiates such as paregoric, tincture of opium, codeine, and morphine.

  5. Paregoric - Wikipedia

    en.wikipedia.org/wiki/Paregoric

    Paregoric was a household remedy in the 18th and 19th centuries when it was widely used to control diarrhea in adults and children, as an expectorant and cough medicine, to calm fretful children, and to rub on the gums to counteract the pain from teething. In a memoir of life in Mississippi after the American Civil War, one woman recalled, "I ...

  6. High doses of ADHD drugs linked to a greater risk of psychosis

    www.aol.com/news/high-doses-adhd-drugs-linked...

    Taking a high dose of ADHD drugs is linked to more than five times greater ... focusing on teens and adults ages 16 to 35 — the typical age range for the onset of psychosis or schizophrenia ...

  7. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Tolerance is a physiologic process where the body adjusts to a medication that is frequently present, usually requiring higher doses of the same medication over time to achieve the same effect. It is a common occurrence in individuals taking high doses of opioids for extended periods, but does not predict any relationship to misuse or addiction.

  8. Opiate - Wikipedia

    en.wikipedia.org/wiki/Opiate

    This occurs even with what are considered modest doses (e.g. ≥25mg oxycodone a day). This may result in the patient to need higher and/or more frequent doses of the drug to get euphoric effects, although it may not be a factor in analgesic effects as tolerance to a dose of opioid does not seem related to loss of efficacy. [34]

  9. Peripherally selective drug - Wikipedia

    en.wikipedia.org/wiki/Peripherally_selective_drug

    Peripherally selective drugs have their primary mechanism of action outside of the central nervous system (CNS), usually because they are excluded from the CNS by the blood–brain barrier. By being excluded from the CNS, drugs may act on the rest of the body without producing side-effects related to their effects on the brain or spinal cord .

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