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Vitamin D regulates proconvulsant and anticonvulsant factors. More specifically, Vitamin D is involved in the down regulation of cytokine IL-6, which is a proconvulsant. [7] Additionally, vitamin D is associated with the up regulation of neurotrophic factors: GDNF and TN3.
There is limited evidence that vitamin D supplementation is of value in alleviating the symptoms of depression in individuals who are vitamin D-deficient. [101] Lithium appears effective at lowering the risk of suicide in those with bipolar disorder and unipolar depression to nearly the same levels as the general population. [217]
With seasonal pattern is a specifier for bipolar and related disorders, including bipolar I disorder and bipolar II disorder. [5] Most people with SAD experience major depressive disorder, but as many as 20% may have a bipolar disorder. It is important to distinguish between diagnoses because there are important treatment differences. [16]
When temperatures drop and sweater weather is in full swing, some people may begin to notice they feel down and not as engaged with the world around them—in part because fewer sunlight hours and ...
Signs of vitamin D deficiency. Fatigue. Mood changes. Muscle pain and weakness. Reduced immune function. Increased inflammation. Frequent infections. Rickets (in children)
Bipolar disorder, previously known as manic depression or manic depressive disorder, ... Certain vitamin deficiencies such as pellagra (niacin deficiency), ...
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