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  2. Thyroid-stimulating hormone - Wikipedia

    en.wikipedia.org/wiki/Thyroid-stimulating_hormone

    Thyroid-stimulating hormone (also known as thyrotropin, thyrotropic hormone, or abbreviated TSH) is a pituitary hormone that stimulates the thyroid gland to produce thyroxine (T 4), and then triiodothyronine (T 3) which stimulates the metabolism of almost every tissue in the body. [1]

  3. Hypothalamic–pituitary–thyroid axis - Wikipedia

    en.wikipedia.org/wiki/Hypothalamic–pituitary...

    The pituitary gland secretes thyrotropin (TSH; Thyroid Stimulating Hormone) that stimulates the thyroid to secrete thyroxine (T4) and, to a lesser degree, triiodothyronine (T3). The major portion of T3, however, is produced in peripheral organs, e.g. liver, adipose tissue, glia and skeletal muscle by deiodination from

  4. Thyroid hormones - Wikipedia

    en.wikipedia.org/wiki/Thyroid_hormones

    Thyroid-stimulating hormone (TSH) released from the anterior pituitary (also known as the adenohypophysis) binds the TSH receptor (a G s protein-coupled receptor) on the basolateral membrane of the cell and stimulates the endocytosis of the colloid. The endocytosed vesicles fuse with the lysosomes of the follicular cell.

  5. Thyrotroph Thyroid Hormone Sensitivity Index - Wikipedia

    en.wikipedia.org/wiki/Thyrotroph_Thyroid_Hormone...

    Sensitivity of TSH-producing pituitary cells to thyroid hormones; also a marker for the set point of thyroid homeostasis The Thyrotroph Thyroid Hormone Sensitivity Index (abbreviated TTSI , also referred to as Thyrotroph T4 Resistance Index or TT4RI ) is a calculated structure parameter of thyroid homeostasis .

  6. Hypothyroidism - Wikipedia

    en.wikipedia.org/wiki/Hypothyroidism

    Blood free thyroxine and TSH levels are monitored to help determine whether the dose is adequate. This is done 4–8 weeks after the start of treatment or a change in levothyroxine dose. Once the adequate replacement dose has been established, the tests can be repeated after 6 and then 12 months, unless there is a change in symptoms. [ 8 ]

  7. Thyroid - Wikipedia

    en.wikipedia.org/wiki/Thyroid

    In such a case a TRH stimulation test, in which TRH is given and TSH levels are measured at 30 and 60-minutes after, may be conducted. [84] T 3 and T 4 can be measured directly. However, as the two thyroid hormones travel bound to other molecules, and it is the "free" component that is biologically active, free T 3 and free T 4 levels can be ...

  8. Thyrotropin receptor - Wikipedia

    en.wikipedia.org/wiki/Thyrotropin_receptor

    The thyrotropin receptor (or TSH receptor) is a receptor (and associated protein) that responds to thyroid-stimulating hormone (also known as "thyrotropin") and stimulates the production of thyroxine (T4) and triiodothyronine (T3). The TSH receptor is a member of the G protein-coupled receptor superfamily of integral membrane proteins [5] and ...

  9. SimThyr - Wikipedia

    en.wikipedia.org/wiki/SimThyr

    SimThyr is a free continuous dynamic simulation program for the pituitary-thyroid feedback control system. [1] The open-source program is based on a nonlinear model of thyroid homeostasis. [ 2 ] [ 3 ] [ 4 ] In addition to simulations in the time domain the software supports various methods of sensitivity analysis .

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