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Miltefosine, sold under the trade name Impavido among others, is a medication mainly used to treat leishmaniasis and free-living amoeba infections such as Naegleria fowleri and Balamuthia mandrillaris. [4] This includes the three forms of leishmaniasis: cutaneous, visceral and mucosal. [5] It may be used with liposomal amphotericin B or ...
Paromomycin is an inexpensive (US$10) and effective treatment for leishmaniasis. The treatment is determined by where the disease is acquired, the species of Leishmania, and the type of infection. [2] For visceral leishmaniasis in India, South America, and the Mediterranean, liposomal amphotericin B is the recommended treatment and is often ...
Leishmania braziliensis, like other species of Leishmania, rely on asexual reproduction in the intermediate mammalian host to greatly increase population density. Such reproduction is often witnessed in mononuclear phagocytes (dendritic cells, monocytes, neutrophils) of the mammalian host, with the macrophages being the target white blood cell of the parasite. [5]
Leishmania / l iː ʃ ˈ m eɪ n i ə,-ˈ m æ n-/ [1] is a parasitic protozoan, a single-celled organism of the genus Leishmania that is responsible for the disease leishmaniasis. [2] [3] [4] They are spread by sandflies of the genus Phlebotomus in the Old World, and of the genus Lutzomyia in the New World.
Leishmania tropica is a flagellate parasite and the cause of anthroponotic [dubious – discuss] cutaneous leishmaniasis in humans. [2] This parasite is restricted to Afro-Eurasia and is a common cause of infection in Afghanistan, Iran, Syria, Yemen, Algeria, Morocco, and northern India. [3]
Cutaneous leishmaniasis is the most common form of leishmaniasis affecting humans. [4] It is a skin infection caused by a single-celled parasite that is transmitted by the bite of a phlebotomine sand fly. There are about thirty species of Leishmania that may cause cutaneous leishmaniasis.
This type does not produce ulcers and there is no treatment. Treatment of Leishmaniasis caused by L. mexicana consists of pentavalent antimonials as Pentostam or Glucantime injected direct into the ulcer or Intramuscular. Prevention of L. mexicana infection is principally avoiding the bite of the infected sandfly.
Meglumine antimoniate is a medicine used to treat leishmaniasis. [1] This includes visceral, mucocutaneous, and cutaneous leishmaniasis. [1] It is given by injection into a muscle or into the area infected. [1] Side effects include loss of appetite, nausea, abdominal pain, cough, feeling tired, muscle pain, irregular heartbeat, and kidney ...