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This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs.
4211 17268 Ensembl ENSG00000143995 ENSMUSG00000020160 UniProt O00470 Q60954 RefSeq (mRNA) NM_002398 NM_001193271 NM_010789 RefSeq (protein) NP_002389 NP_001180200 NP_034919 Location (UCSC) Chr 2: 66.43 – 66.57 Mb Chr 11: 18.83 – 18.97 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Homeobox protein Meis1 is a protein that in humans is encoded by the MEIS1 gene. Function Homeobox ...
MEF2, Myocyte Enhancer Factor 2, is a transcription factor with four specific numbers such as MEF2A, B, C, and D. Each MEF2 gene is located on a specific chromosome. MEF2 is known to be involved in the development and the looping of the heart (Chen) MEF2 is necessary for myocyte differentiation and gene activation (Black).
Activation of gene transcription is a complex system of signal cascades and recruitment of necessary components such as RNA polymerase and transcription factors. IEGs are often the first responders to regulatory signals with many reaching peak expression within 30 minutes after stimuli compared to 2–4 hours in the case of delayed primary ...
The mechanism of saRNA-mediated RNAa centers around the RNA-induced transcriptional activation (RITA) complex. [17] This complex includes: Argonaute 2 (AGO2): AGO2 binds to the guide strand of the saRNA and facilitates targeting to the gene promoter. AGO2 is the primary Argonaute protein involved in saRNA-mediated RNAa.
Structure of a gene regulatory network Control process of a gene regulatory network. A gene (or genetic) regulatory network (GRN) is a collection of molecular regulators that interact with each other and with other substances in the cell to govern the gene expression levels of mRNA and proteins which, in turn, determine the function of the cell.
30062 19434 Ensembl ENSG00000134438 ENSMUSG00000024518 UniProt Q9Y2V3 O35602 RefSeq (mRNA) NM_013435 NM_013833 RefSeq (protein) NP_038463 NP_038861 Location (UCSC) Chr 18: 59.27 – 59.27 Mb Chr 18: 66.06 – 66.07 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Retinal homeobox protein Rx also known as retina and anterior neural fold homeobox is a protein that in humans is encoded ...
Myocyte-specific enhancer factor 2C also known as MADS box transcription enhancer factor 2, polypeptide C is a protein that in humans is encoded by the MEF2C gene. [ 4 ] [ 5 ] MEF2C is a transcription factor in the Mef2 family.