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Anaphylactoid reaction, non-immune anaphylaxis, or pseudoanaphylaxis, is a type of anaphylaxis that does not involve an allergic reaction but is due to direct mast cell degranulation. [ 10 ] [ 42 ] Non-immune anaphylaxis is the current term, as of 2018, used by the World Allergy Organization [ 42 ] with some recommending that the old ...
Mosquito bite allergies are informally classified as 1) the skeeter syndrome, i.e., severe local skin reactions sometimes associated with low-grade fever; 2) systemic reactions that range from high-grade fever, lymphadenopathy, abdominal pain, and/or diarrhea to, very rarely, life-threatening symptoms of anaphylaxis; and 3) severe and often ...
If multiple systems are involved, then anaphylaxis can take place, which is an acute, systemic reaction that can prove fatal. Treatment usually involves adrenaline ( epinephrine ) because it counteracts anaphylaxis by increasing blood flow and relaxing bronchial muscles that block one’s airways. [ 7 ]
The treatment of immediate hypersensitivity reactions includes the management of anaphylaxis with intramuscular adrenaline (epinephrine), oxygen, intravenous (IV) antihistamine, support blood pressure with IV fluids, avoid latex gloves and equipment in patients who are allergic, and surgical procedures such as tracheotomy if there is severe ...
Management of drug allergy consists principally of avoidance or discontinuation of the causative drug. [6] Treatment is largely supportive and symptomatic. [6] It may consist of topical corticosteroids and oral antihistamines for cutaneous symptoms such as hives and itching. [6] Mild cutaneous reactions can be managed with antihistamines only. [6]
In Australia, hospital admission rates for food-induced anaphylaxis increased by an average of 13.2% from 1994-2005. [93] One possible explanation for the rise in food allergy is the "old friends" hypothesis, which suggests that non-disease-causing organisms, such as helminths , could protect against allergy.
Cromolyn Nedocromil. Mast cell stabilizers are medications used to prevent or treat certain allergic disorders. They block mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine and related mediators.
A flowchart depicting the events of acute inflammation. [23] Micrograph showing granulation tissue. H&E stain. The process of acute inflammation is initiated by resident immune cells already present in the involved tissue, mainly resident macrophages, dendritic cells, histiocytes, Kupffer cells and mast cells.