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2. Uricosuric - Wikipedia

   en.wikipedia.org/wiki/Uricosuric

   By decreasing plasma uric acid levels, help dissolve these crystals, while limiting the formation of new ones. However, the increased uric acid levels in urine can contribute to kidney stones . Thus, use of these drugs is contraindicated in persons already with a high urine concentration of uric acid ( hyperuricosuria ).

3. Your Gout Guide: From Symptoms to Treatment - AOL

   www.aol.com/gout-guide-symptoms-treatment...

   Uric acid is a normal waste product made by the body, but in some people, it can accumulate at higher levels and lead to gout. ... they may recommend using medications to reduce your symptoms ...

4. Allopurinol - Wikipedia

   en.wikipedia.org/wiki/Allopurinol

   Allopurinol is used to reduce urate formation in conditions where urate deposition has already occurred or is predictable. The specific diseases and conditions where it is used include gouty arthritis, skin tophi, kidney stones, idiopathic gout; uric acid lithiasis; acute uric acid nephropathy; neoplastic disease and myeloproliferative disease with high cell turnover rates, in which high urate ...

5. Thiazide - Wikipedia

   en.wikipedia.org/wiki/Thiazide

   Hypokalemia – Thiazide diuretics reduce potassium concentration in blood through two indirect mechanisms: inhibition of sodium-chloride symporter at distal convoluted tubule of a nephron and stimulation of aldosterone that activates Na+/K+-ATPase at collecting duct. Inhibition of sodium-chloride symporter increases availability of sodium and ...

6. Uric acid - Wikipedia

   en.wikipedia.org/wiki/Uric_acid

   Uric acid displays lactam–lactim tautomerism. [4] Uric acid crystallizes in the lactam form, [5] with computational chemistry also indicating that tautomer to be the most stable. [6] Uric acid is a diprotic acid with pK a1 = 5.4 and pK a2 = 10.3. [7] At physiological pH, urate predominates in solution. [medical citation needed]

7. Methenamine - Wikipedia

   en.wikipedia.org/wiki/Methenamine

   Methenamine is provided medically as the hippuric acid or mandelic acid salt, and the acid salt component plays a key role in helping to make the urine more acidic such that the activity of methenamine is optimized. [2] [3] [9] [30] Ascorbic acid (vitamin C), sodium acid phosphate, or ammonium chloride can also be supplemented to further ...