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In 1971, Barry Pressman and Henry Burdick launched Nature Made, inspired by the belief that “there was a better alternative to long term health than prescription drugs.” [1] [2] The company joined the Council for Responsible Nutrition (CRN) in 1981. [2] Nature Made began operating as a brand of Pharmavite as of this date.
Several forms of vitamin D exist, with the two major forms being vitamin D 2 or ergocalciferol, and vitamin D 3 or cholecalciferol. [1]The common-use term "vitamin D" refers to both D 2 and D 3, which were chemically characterized, respectively, in 1931 and 1935.
Vitamin D compounds, specifically cholecalciferol (D3) and ergocalciferol (D2), are used in rodenticides due to their ability to induce hypercalcemia, a condition characterized by elevated calcium levels in the blood. This overdose leads to organ failure and is pharmacologically similar to vitamin D's toxic effects in humans.
Doses greater than 40 000 IU (1000 μg) per day are generally required before high blood calcium occurs. [12] Normal doses, 800–2000 IU per day, are safe in pregnancy. [5] Cholecalciferol was first described in 1936. [13] It is on the World Health Organization's List of Essential Medicines. [14]
Ergocalciferol, also known as vitamin D 2 and nonspecifically calciferol, is a type of vitamin D found in food. It is used as a dietary supplement [3] to prevent and treat vitamin D deficiency [4] due to poor absorption by the intestines or liver disease. [5]
Biden made history as the first FLOTUS in the role's 231-year history preceding her to keep her day job while serving in the White House as the first lady. She has four degrees, including two ...
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