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Aplastic anemia [2] (AA) [3] is a severe hematologic condition in which the body fails to make blood cells in sufficient numbers. Blood cells are produced in the bone marrow by stem cells that reside there. [4] Aplastic anemia causes a deficiency of all blood cell types: red blood cells, white blood cells, and platelets. [5] [6]
Pure red cell aplasia (PRCA) or erythroblastopenia refers to a type of aplastic anemia affecting the precursors to red blood cells but usually not to white blood cells. In PRCA, the bone marrow ceases to produce red blood cells. There are multiple etiologies that can cause PRCA. The condition has been first described by Paul Kaznelson in 1922. [1]
This is a life-threatening disorder that is a characteristic of aplastic anemia. [3] There are also two general causes of cytopenia: autoimmune and refractory. Autoimmune cytopenia is caused by an autoimmune disease when your body produces antibodies to destroy the healthy blood cells.
Aplastic anemia is a condition where bone marrow does not produce sufficient new cells to replenish blood cells. [27] Autoimmune hemolytic anemia: D59.0-D59.1: Autoimmune hemolytic anemia (AIHA) is a type of hemolytic anemia where the body's immune system attacks its own red blood cells (RBCs), leading to their destruction .
"The mystery has finally been solved," Congo's health ministry says, after an unidentified disease outbreak started killing mainly women and children in a remote region.
If pancytopenia is present, bone marrow failure [4] must be considered and evaluation for bone marrow failure syndromes or aplastic anemia must be pursued. Treatment is dependent on the etiology and may include replacement of blood products as patients can develop severe anemia. [3]
The Environmental Protection Agency has labeled inorganic arsenic a carcinogen, or a substance that causes cancer. Massive winter storm expected to bring heavy snow, ice, cold to 25 states.
"This causes recurrent episodes of coughing, wheezing, and chest tightness," says Dr. Laura Conrad, director of the Pediatric Asthma Center at the Children’s Hospital at Montefiore in New York.