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Cariprazine, sold under the brand name Vraylar among others, is an atypical antipsychotic developed by Gedeon Richter, [8] which is used in the treatment of schizophrenia, bipolar mania, [9] bipolar depression, [10] and major depressive disorder. [6] It acts primarily as a D 3 and D 2 receptor partial agonist, with a preference for the D 3 ...
Akathisia (IPA: /æ.kə.ˈθɪ.si.ə/) is a movement disorder [5] characterized by a subjective feeling of inner restlessness accompanied by mental distress and/or an ...
Vraylar (cariprazine) – atypical antipsychotic used to treat schizophrenia and bipolar mania; W. Wellbutrin IR, SR or XL – an antidepressant of the ...
Currently approved antipsychotic drugs include Vanda Pharmaceuticals' Fanapt, AbbVie's Vraylar and generic drugs such as olanzapine, quetiapine and aripiprazole, among others.
Long-term use can produce adverse effects such as tardive dyskinesia, tardive dystonia, and tardive akathisia. First-generation antipsychotics (e.g., chlorpromazine , haloperidol , etc.), known as typical antipsychotics , were first introduced in the 1950s, and others were developed until the early 1970s. [ 12 ]
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
Bristol Myers' Pomalyst and two other Abbvie drugs, Vraylar and Venclexta, may also be up for negotiation in 2027, analysts said. "We are proud of the 10 agreements reached to bring new, lower ...
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