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Midazolam (Versed) is given at the onset of anesthesia and has been shown in recent trials to be as effective as ondansetron, but most effective when used in combination with ondansetron. [15] Lorazepam (Ativan) is said to be very good as an adjunct treatment for nausea along with first line medications such as Compazine. [citation needed]
Ondansetron, sold under the brand name Zofran among others, is a medication used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, migraines, or surgery. [8] It is also effective for treating gastroenteritis. [9] [10] It can be given orally (by mouth), intramuscularly (injection into a muscle), or intravenously ...
The development of selective 5-HT 3 receptor antagonists was a dramatic improvement in the treatment of nausea and vomiting. [30] Ondansetron, granisetron, dolasetron and palonosetron are currently approved in the United States, and form the cornerstone of therapy for the control of acute emesis with chemotherapy agents with moderate to high ...
Another subclass consists of drugs selectively acting at the 5-HT 3 receptors, and thus are known as 5-HT 3 antagonists. They are efficacious in treating chemotherapy-induced emesis and postoperative nausea and vomiting. [1] They include, but are not limited to: Dolasetron; Granisetron; Ondansetron; Palonosetron; Tropisetron
These drugs block one or more of the nerve signals that cause nausea and vomiting. During the first 24 hours after chemotherapy, the most effective approach appears to be blocking the 5-HT 3 nerve signal. [10] Approved 5-HT 3 inhibitors include dolasetron (Anzemet), granisetron (Kytril, Sancuso), and ondansetron (Zofran). Their antiemetic ...
Usually pain relieving drugs such as opioids are co-prescribed with anti-emetic drugs to stop the emetic response due to the pain reliever before it can even mediate its effects on the CTZ. This way, the patient does not have to worry about the doctors prescription to treat their pain causing them to be in severe discomfort via vomiting.
Aprepitant, sold under the brand name Emend among others, is a medication used to prevent chemotherapy-induced nausea and vomiting and to prevent postoperative nausea and vomiting. [5] It may be used together with ondansetron and dexamethasone. [5] It is taken by mouth [5] or administered by intravenous injection. [3]
Nausea is a side effect of many medications including chemotherapy, or morning sickness in early pregnancy. Nausea may also be caused by disgust and depression. [1] Medications taken to prevent and treat nausea and vomiting are called antiemetics.
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