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Medication for Anxiety: A Complete Guide. As you probably know from personal experience, anxiety can be a lot of things — a cause of insomnia, a roadblock to living your best life or a demon you ...
Buspirone, sold under the brand name Buspar among others, is an anxiolytic, a medication primarily used to treat anxiety disorders, particularly generalized anxiety disorder (GAD). [ 10 ] [ 11 ] It is a serotonin 5-HT 1A receptor partial agonist , increasing action at serotonin receptors in the brain. [ 3 ]
Buspirone can be useful in GAD but not particularly effective in treating phobias, panic disorder or social anxiety disorders. [2] It is a safer option for long-term use as it does not cause dependence like benzodiazepines.
Key symptoms include excessive anxiety about multiple events and issues, and difficulty controlling worrisome thoughts, that persists for at least 6 months. Antidepressants provide a modest-to-moderate reduction in anxiety in GAD, [25] and are superior to placebo in treating GAD. The efficacy of different antidepressants is similar.
Treatments may include a type of antidepressant called selective serotonin reuptake inhibitors (SSRIs), beta-blockers (to reduce the physical symptoms associated with anxiety), or benzodiazepines ...
Azapirones have shown benefit in general anxiety [14] and augmenting SSRIs in social anxiety [15] and depression. [16] Evidence is not clear for panic disorder [17] and functional gastrointestinal disorders. [18] Tandospirone has also been used to augment antipsychotics in Japan as it improves cognitive and negative symptoms of schizophrenia. [19]
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